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公开(公告)号：US20220016131A1
公开(公告)日：2022-01-20
申请号：US17371750
申请日：2021-07-09
IPC分类号： A61K31/551 , A61K31/506 , A61P35/00
摘要： Among the various aspects of the present disclosure is the provision of a methods for increasing chemotherapy sensitivity or decreasing chemotherapy resistance using BET inhibitors.
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公开(公告)号：US11938138B2
公开(公告)日：2024-03-26
申请号：US17371750
申请日：2021-07-09
IPC分类号： A61P35/00 , A61K31/506 , A61K31/551
CPC分类号： A61K31/551 , A61K31/506 , A61P35/00
摘要： Among the various aspects of the present disclosure is the provision of a methods for increasing chemotherapy sensitivity or decreasing chemotherapy resistance using BET inhibitors.
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3.发明申请公开(公告)号：US20200181626A1
公开(公告)日：2020-06-11
申请号：US16711011
申请日：2019-12-11
IPC分类号： C12N15/63 , C12N15/90 , C12N15/113 , C12N15/10 , C12N9/22
摘要： Among the various aspects of the present disclosure is the provision of compositions and methods for mapping transposon insertions. Applications can include mapping the locations of self-reporting transposons (SRTs) from thousands of single cells in parallel, while simultaneously measuring mRNA abundance from the same single cells; analyzing genome-associated protein (GAP) (e.g., transcription factor) binding/interactions in a small number of cells in bulk, without single cell resolution; lineage tracing; or as an improved readout for transposon mutagenesis screens.
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