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公开(公告)号：US06998250B2
公开(公告)日：2006-02-14
申请号：US09977667
申请日：2001-10-15
申请人： Donald J. McMichael , Kristy Peterson , Barry J. Marshall , Aruni H. W. Mendis , Simon Chairman
发明人： Donald J. McMichael , Kristy Peterson , Barry J. Marshall , Aruni H. W. Mendis , Simon Chairman
IPC分类号： C12Q1/04
摘要： A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. The system includes a carrier having a first well and a second well. A first composition is disposed in the first well and contains urea in powdered form. A second composition is disposed in a second well and contains an indicator. A biopsy of a gastric sample is manipulated with a specimen-handling tool and is first contacted with the first composition and then placed in the second composition. The second composition indicates the presence of an enzyme, which, in turn, indicates the presence of bacteria.
摘要翻译： 公开了一种用于检测胃肠道细菌感染的系统和方法。 该系统包括具有第一井和第二井的载体。 第一组合物设置在第一孔中并含有粉末状的尿素。 第二组合物设置在第二孔中并且包含指示剂。 用样品处理工具操作胃样品的活组织检查，并首先与第一组合物接触，然后置于第二组合物中。 第二组合物表示酶的存在，其反过来指示细菌的存在。
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公开(公告)号：US07087398B2
公开(公告)日：2006-08-08
申请号：US09977555
申请日：2001-10-15
IPC分类号： C12Q1/58
摘要： A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. In one embodiment, the system includes a first composition separated from a second composition. The first composition contains urea in powdered form. The second composition, on the other hand, contains an indicator. A biopsy of a gastric sample is first contacted with the first composition and then placed in the second composition. The second composition indicates the presence of an enzyme that, in turn, indicates the presence of bacteria. In an alternative embodiment of the present invention, a biopsy of a gastric sample is contacted with a single composition. The composition contains urea in a powdered form combined with a dry indicator. Besides urea and a dry indicator, the composition can also contain an anti-caking agent.
摘要翻译： 公开了一种用于检测胃肠道细菌感染的系统和方法。 在一个实施方案中，该系统包括与第二组合物分离的第一组合物。 第一组合物含有粉末形式的尿素。 另一方面，第二种组合包含指示剂。 首先将胃样品的活组织检查与第一组合物接触，然后置于第二组合物中。 第二组合物表明存在酶，其反过来表明存在细菌。 在本发明的另一个实施方案中，胃样品的活检与单一组合物接触。 组合物含有与干指示剂组合的粉末形式的尿素。 除了尿素和干指示剂之外，组合物还可以含有抗结块剂。
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公开(公告)号：US07008777B2
公开(公告)日：2006-03-07
申请号：US09977556
申请日：2001-10-15
IPC分类号： C12Q1/58
摘要： A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. In one embodiment, the system includes a first composition separated from a second composition. The first composition contains urea in powdered form. The second composition, on the other hand, contains an indicator. A biopsy of a gastric sample is first contacted with the first composition and then placed in the second composition. The second composition indicates the presence of an enzyme that, in turn, indicates the presence of bacteria. In an alternative embodiment of the present invention, a biopsy of a gastric sample is contacted with a single composition. The composition contains urea in a powdered form combined with a dry indicator. Besides urea and a dry indicator, the composition can also contain an anti-caking agent.
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公开(公告)号：US06929926B2
公开(公告)日：2005-08-16
申请号：US09977874
申请日：2001-10-15
摘要： A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. In one embodiment, the system includes a first composition separated from a second composition. The first composition contains urea in powdered form. The second composition, on the other hand, contains an indicator. A biopsy of a gastric sample is first contacted with the first composition and then placed in the second composition. The second composition indicates the presence of an enzyme that, in turn, indicates the presence of bacteria. In an alternative embodiment of the present invention, a biopsy of a gastric sample is contacted with a single composition. The composition contains urea in a powdered form combined with a dry indicator. Besides urea and a dry indicator, the composition can also contain an anti-caking agent.
摘要翻译： 公开了一种用于检测胃肠道细菌感染的系统和方法。 在一个实施方案中，该系统包括与第二组合物分离的第一组合物。 第一组合物含有粉末形式的尿素。 另一方面，第二种组合包含指示剂。 首先将胃样品的活组织检查与第一组合物接触，然后置于第二组合物中。 第二组合物表明存在酶，其反过来表明存在细菌。 在本发明的另一个实施方案中，胃样品的活检与单一组合物接触。 组合物含有与干指示剂组合的粉末形式的尿素。 除了尿素和干指示剂之外，组合物还可以含有抗结块剂。
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