公开(公告)号：US5977152A

公开(公告)日：1999-11-02

申请号：US944304

申请日：1997-10-06

申请人： Sadao Oida ,  Teruo Tanaka ,  Yawara Tajima ,  Toshiyuki Konosu ,  Atsushi Somada ,  Takeo Miyaoka ,  Hiroshi Yasuda

发明人： Sadao Oida ,  Teruo Tanaka ,  Yawara Tajima ,  Toshiyuki Konosu ,  Atsushi Somada ,  Takeo Miyaoka ,  Hiroshi Yasuda

IPC分类号： A01N43/653 ,  A61K31/4196 ,  C07D249/08 ,  C07D401/12 ,  C07D409/12 ,  C07D521/00 ,  A61K31/41

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： A triazole compound having the formula: ##STR1## wherein Ar.sup.1 represents an optionally substituted phenyl, Ar.sup.2 represents an optionally substituted phenyl, R.sup.0 represents a hydrogen atom or a lower alkyl; R.sup.1 represents a lower alkyl; R.sup.2 to R.sup.5 represent a hydrogen atom or an unsubstituted or halo substituted alkyl, n represents 0 to 2; p represents 0 or 1; q, r and s each represent 0 to 2; and A represents a 1,3-dioxan-5-yl. The triazole compound of the present invention exhibits an excellent antifungal activity.

摘要翻译： 具有下式的三唑化合物：其中Ar 1表示任选取代的苯基，Ar 2表示任选取代的苯基，R 0表示氢原子或低级烷基; R1代表低级烷基; R 2至R 5表示氢原子或未取代或卤素取代的烷基，n表示0至2; p表示0或1; q，r和s各自表示0〜2; A代表1,3-二恶烷-5-基。 本发明的三唑化合物表现出优异的抗真菌活性。

公开(公告)号：US06306880B1

公开(公告)日：2001-10-23

申请号：US09241370

申请日：1999-02-01

申请人： Sadao Oida ,  Teruo Tanaka ,  Yawara Tajima ,  Toshiyuki Konosu ,  Atsushi Somada ,  Takeo Miyaoka ,  Hiroshi Yasuda

发明人： Sadao Oida ,  Teruo Tanaka ,  Yawara Tajima ,  Toshiyuki Konosu ,  Atsushi Somada ,  Takeo Miyaoka ,  Hiroshi Yasuda

IPC分类号： C07D40112

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： A triazole compound having the formula: wherein Ar1 represents a phenyl group which may be substituted; Ar2 represents a phenyl group which may be substituted; R0 represents a hydrogen atom or a lower alkyl; R1 represents a lower alkyl; R2 to R5 each represnet a hydrogen atom or an unsubstituted or halo substituted alkyl; n represnets 0 to 2; p represents 0 or 1; q, r and s each represent 0 to 2; A represents a 4- to 7-membered carbon ring or a 4- to 7-membered heterocyclic, not including 1,3-dioxan-5-yl. The compound of the present invention exhibits an excellent antifungal activity.

摘要翻译： 具有下式的三唑化合物：其中Ar 1表示可被取代的苯基; Ar2表示可以被取代的苯基; R 0表示氢原子或低级烷基; R1代表低级烷基; R2至R5各自代表氢原子或未取代或卤代取代的烷基; n表示0到2; p表示0或1; q，r和s各自表示0〜2; A代表4-至7-元碳环或4-至7-元杂环，不包括1,3-二恶烷-5-基。 本发明的化合物显示出优异的抗真菌活性。

公开(公告)号：US06300357B1

公开(公告)日：2001-10-09

申请号：US09241369

申请日：1999-02-01

申请人： Sadao Oida ,  Teruo Tanaka ,  Yawara Tajima ,  Toshiyuki Konosu ,  Atsushi Somada ,  Takeo Miyaoka ,  Hiroshi Yasuda

发明人： Sadao Oida ,  Teruo Tanaka ,  Yawara Tajima ,  Toshiyuki Konosu ,  Atsushi Somada ,  Takeo Miyaoka ,  Hiroshi Yasuda

IPC分类号： C07D24908

CPC分类号： C07D231/12 ,  A01N43/653 ,  C07D233/56 ,  C07D249/08

摘要： A triazole compound having the formula: wherein Ar1 represents a phenyl group which may be substituted, Ar2 represents a heterocyclic group which may be substituted, R0 represents a hydrogen atom or a lower alkyl; R1 represents a lower alkyl; R2 to R5 each represent a hydrogen atom or an unsubstituted or halo substituted alkyl; n represents 0 to 2; p represents 0 or 1; q, r and s each represent 0 to 2; A represents a 4- to 7-membered carbon ring or a 4- to 7-membered heterocyclic group. The compound of the present invention exhibits an excellent antifungal activity.

摘要翻译： 具有下式的三唑化合物：其中Ar1表示可被取代的苯基，Ar2表示可被取代的杂环基，R0表示氢原子或低级烷基; R1代表低级烷基; R 2至R 5各自表示氢原子或未取代或卤素取代的烷基; n表示0〜2; p表示0或1; q，r和s各自表示0〜2; A表示4-至7-元碳环或4-至7-元杂环基。 本发明的化合物显示出优异的抗真菌活性。