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1.发明公开公开(公告)号：US20230248667A1
公开(公告)日：2023-08-10
申请号：US18105795
申请日：2023-02-03
申请人： Aurobindo Pharma Ltd
发明人： Soumyajit Behera , Satheesh Kumar Gajjala , Nilesh Bhandari , Nagaprasad Vishnubhotla , Sivakumaran Meenakshisunderam
IPC分类号： A61K31/137 , A61K31/495 , A61K9/28
CPC分类号： A61K31/137 , A61K31/495 , A61K9/2893 , A61K9/2866 , A61K9/282
摘要： This invention relates to dosage forms comprising pseudoephedrine or a salt thereof, for extended-release up to 24 hours, and process of making such dosage forms. This invention provides a non-osmotic extended-release dosage form comprising pseudoephedrine hydrochloride which can be administered to patients who need and/or desire a decongestant medication up to 24 hours. This invention also relates to dosage forms comprising pseudoephedrine or a salt thereof and cetirizine or levocetirizine or its salts thereof for extended-release up to 24 hours, and process of making such dosage forms.
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2.发明申请公开(公告)号：US20210177822A1
公开(公告)日：2021-06-17
申请号：US17119250
申请日：2020-12-11
IPC分类号： A61K31/4468 , A61K9/48 , A61K9/00
摘要： The present invention relates to prepare pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof, processes for manufacturing said pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof. Also pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis.
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公开(公告)号：US20180008547A1
公开(公告)日：2018-01-11
申请号：US15548063
申请日：2016-02-01
申请人： Shridhar INAGANTI , Venugopala CHOKKASANDRA JAYARAMA REDDY , Jayant KARAJGI , Sivakumaran MEENAKSHISUNDERAM , AUROBINDO PHARMA LTD
发明人： Shridhar Inaganti , Venugopala Chokkasandra Jayarama Reddy , Jayant Karajgi , Sivakumaran Meenakshisunderam
CPC分类号： A61K9/4808 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K38/10
摘要： The present invention relates to stable oral composition comprising linaclotide or its pharmaceutically acceptable salts, complexes, polymorphs, hydrates, solvates, enantiomers or racemates, process of preparation thereof and methods of using the same.
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公开(公告)号：US10308611B2
公开(公告)日：2019-06-04
申请号：US15741722
申请日：2016-03-18
申请人： AUROBINDO PHARMA LTD
发明人： Sukumar Nandi , Akkina Naresh , Syam Prasad Reddy Rao Annareddy , Gona Bala Narsimha Reddy , Meenakshi Sunderam Sivakumaran
IPC分类号： C07D223/16
摘要： The present invention provides a process for the preparation of crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia), which comprises, Formula (Ia) (i) providing a solution of Lorcaserin base in a solvent; (ii) if water is present, removing water from the reaction mixture; (iii) adding hydrogen chloride to the reaction mixture; (iv) combining the reaction mixture with a suitable anti-solvent; and (v) isolating the crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia).
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5.发明申请公开(公告)号：US20190070120A1
公开(公告)日：2019-03-07
申请号：US16083534
申请日：2017-03-09
IPC分类号： A61K9/20 , A61K9/28 , A61K31/7042 , A61P3/04 , A61P3/10
摘要： The present invention relates to a binder tree pharmaceutical composition comprising canagliflozin or a prodrug or a pharmaceutically acceptable salt thereof, and one or more 5 pharmaceutically acceptable excipients, wherein the said composition is devoid of canagliflozin hemihydrate, and having acceptable chemical stability, polymorphic stability & comparative dissolution and bioequivalence profile to that of INVOKANA® tablets.
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公开(公告)号：US20190023706A1
公开(公告)日：2019-01-24
申请号：US16081944
申请日：2017-02-24
申请人： Sandeep JAIN , Komel ANSARI , Subramanyam MADDALA , Sivakumaran MEENAKSHISUNDERAM , AUROBINDO PHARMA LTD
IPC分类号： C07D473/18
摘要： The present invention relates to an improved process for the preparation of Valacyclovir or pharmaceutically acceptable salts thereof, which comprises reaction of amine-protected Valacyclovir or its salt with deprotecting agent in a continuous flow reactor.
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7.发明授权公开(公告)号：US11648242B2
公开(公告)日：2023-05-16
申请号：US17119250
申请日：2020-12-11
IPC分类号： A61K31/4468 , A61K9/48 , A61K9/00
CPC分类号： A61K31/4468 , A61K9/0053 , A61K9/485 , A61K9/4833 , A61K9/4858 , A61K9/4866
摘要： The present invention relates to prepare pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof, processes for manufacturing said pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof. Also pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis.
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公开(公告)号：US20200253955A1
公开(公告)日：2020-08-13
申请号：US16462856
申请日：2017-11-22
申请人： Aurobindo Pharma Ltd
发明人： Rama Shankar , Nimesh Chandra Misra , Siva Rama Kasibabu Velegula , Suresh Chapala , Sivakumaran Meenakshisunderam
IPC分类号： A61K31/485
摘要： The present invention relates to solid dispersion of Naloxegol oxalate. Further, the present invention relates to an improved process for Naloxegol oxalate and intermediates thereof.
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公开(公告)号：US20180194743A1
公开(公告)日：2018-07-12
申请号：US15741859
申请日：2016-05-09
发明人： Sukumar Nandi , Shantan Kumar Reddy , Gona Bala Narashimha Reddy , Sivakumaran Meenakshisundaram
IPC分类号： C07D277/40
CPC分类号： C07D277/40
摘要： The present invention provides a process for the preparation of α-Form crystals of Mirabegron using a solvent selected from water.
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公开(公告)号：US20180194734A1
公开(公告)日：2018-07-12
申请号：US15741722
申请日：2016-03-18
申请人： AUROBINDO PHARMA LTD
发明人： Sukumar Nandi , Akkina Naresh , Syam Prasad Reddy Rao Annareddy , Gona Bala Narsimha Reddy , Meenakshi Sunderam Sivakumaran
IPC分类号： C07D223/16
CPC分类号： C07D223/16 , C07B2200/13
摘要： The present invention provides a process for the preparation of crystalline Lorcaserin hydrochloride hemihydrate of Formula (1a), which comprises, Formula (1a) (i) providing a solution of Lorcaserin base in a solvent; (ii) if water is present, removing water from the reaction mixture; (iii) adding hydrogen chloride to the reaction mixture; (iv) combining the reaction mixture with a suitable anti-solvent; and (v) isolating the crystalline Lorcaserin hydrochloride hemihydrate of Formula (1a).
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