公开(公告)号：US11007376B2

公开(公告)日：2021-05-18

申请号：US16262682

申请日：2019-01-30

申请人： BeneSol, Inc.

发明人： William A. Moffat, IV

IPC分类号： A61N5/06

摘要： The present disclosure is directed to a phototherapeutic apparatus for focused UVB radiation and vitamin D synthesis and associated systems methods. In one embodiment a phototherapeutic apparatus can include a housing at least partially defining an irradiation zone, and an ultraviolet (UV) radiation source carried by the housing. The irradiation zone can be configured to accommodate at least a portion of a human patient. The phototherapeutic apparatus can further include a filter between the UV radiation source and the irradiation zone. The filter can be configured to at least substantially remove UV radiation outside of a predetermined spectrum centered at about 297 nm and having a bandwidth of at most 10 nm.

公开(公告)号：US20180353770A1

公开(公告)日：2018-12-13

申请号：US15569019

申请日：2016-04-27

申请人： BENESOL, INC.

发明人： William A. Moffat

IPC分类号： A61N5/06

CPC分类号： A61N5/0616 ,  A61N5/06 ,  A61N5/0613 ,  A61N2005/0626 ,  A61N2005/0641 ,  A61N2005/0645 ,  A61N2005/0652 ,  A61N2005/0654 ,  A61N2005/0661 ,  A61N2005/0667 ,  G01J3/42 ,  G01J3/50

摘要： The present disclosure is directed to systems and methods for targeted UVB phototherapy for treating autoimmune disorders and other indications. In one embodiment, a phototherapeutic system can include a radiation source configured to emit light. At least 75% of the light emitted by the radiation source can have a target wavelength range with a bandwidth between 298 nm and 307 nm. The phototherapeutic system can also include a controller operably connected to the radiation source and configured to determine a dosage for a phototherapy session. Dosage can correspond to a product of the intensity of the radiation source and an exposure time of the radiation source, and may have an upper bound less than 1 minimal erythema dose (MED). Delivery of the dose of phototherapy can stimulate an immune response to treat an autoimmune disorder.

公开(公告)号：US20220249863A1

公开(公告)日：2022-08-11

申请号：US17728797

申请日：2022-04-25

申请人： BeneSol, Inc.

发明人： William Alexander Moffat ,  Sen Wen ,  Linda Cox Arnsdorf ,  Eben Lynn Falconer Calhoun ,  Chieh-en Wu

IPC分类号： A61N5/06 ,  G06F3/048 ,  G16H20/40 ,  G16H20/13 ,  G06N20/00 ,  A61B5/00

摘要： Dynamic dosing systems for phototherapy and associated devices, systems, and methods are disclosed herein. In some embodiments, a dynamic dosing phototherapy system can include a self-service phototherapy kiosk (“SPK”) configured to emit UV radiation, a user interface communicatively coupled to the SPK, and a dynamic dosing system communicatively coupled to the user interface and the SPK. The dynamic dosing system can determine initial, user-specific parameters specific to define a first individual phototherapy protocol, and then determine adjustments to the initial parameters and the first individual phototherapy protocol based on user inputs related to erythema response to a previous phototherapy treatment session. The SPK can deliver UV radiation to a user in accordance with the first individual phototherapy protocol and/or an adjusted, second phototherapy protocol that takes into account the user's erythema response.

公开(公告)号：US20210260402A1

公开(公告)日：2021-08-26

申请号：US17315682

申请日：2021-05-10

申请人： BeneSol, Inc.

发明人： William A. Moffat, IV

IPC分类号： A61N5/06

摘要： The present disclosure is directed to a phototherapeutic apparatus for focused UVB radiation and vitamin D synthesis and associated systems methods. In one embodiment a phototherapeutic apparatus can include a housing at least partially defining an irradiation zone, and an ultraviolet (UV) radiation source carried by the housing. The irradiation zone can be configured to accommodate at least a portion of a human patient. The phototherapeutic apparatus can further include a filter between the UV radiation source and the irradiation zone. The filter can be configured to at least substantially remove UV radiation outside of a predetermined spectrum centered at about 297 nm and having a bandwidth of at most 10 nm.

公开(公告)号：US20200376292A1

公开(公告)日：2020-12-03

申请号：US16954075

申请日：2018-12-13

申请人： BeneSol, Inc.

发明人： William Alexander Moffat ,  Sen Wen ,  Linda Cox Arnsdorf ,  Eben Lynn Falconer Calhoun

IPC分类号： A61N5/06 ,  G06F3/048

摘要： Dynamic dosing systems for phototherapy and associated devices, systems, and methods are disclosed herein. In some embodiments, a dynamic dosing phototherapy system can include a self-service phototherapy kiosk (“SPK”) configured to emit UV radiation, a user interface communicatively coupled to the SPK, and a dynamic dosing system communicatively coupled to the user interface and the SPK. The dynamic dosing system can determine initial, user-specific parameters specific to define a first individual phototherapy protocol, and then determine adjustments to the initial parameters and the first individual phototherapy protocol based on user inputs related to erythema response to a previous phototherapy treatment session. The SPK can deliver UV radiation to a user in accordance with the first individual phototherapy protocol and/or an adjusted, second phototherapy protocol that takes into account the user's erythema response.

公开(公告)号：US20180133503A1

公开(公告)日：2018-05-17

申请号：US15817011

申请日：2017-11-17

申请人： BENESOL, INC.

发明人： William A. Moffat

IPC分类号： A61N5/06

CPC分类号： A61N5/0616 ,  A61N5/0613 ,  A61N2005/0627 ,  A61N2005/064 ,  A61N2005/0652 ,  A61N2005/0654 ,  A61N2005/0661 ,  A61N2005/0665 ,  A61N2005/0667

摘要： The present disclosure is directed to systems and methods for increased vitamin D3 production during phototherapy treatments. In one embodiment, a phototherapeutic system can include an ultraviolet (UV) source directed toward an irradiation zone and a filter between the UV source and the irradiation zone. The UV source can be configured to deliver a predetermined energy level during a phototherapy session. The filter can at least substantially remove UV radiation outside of a predetermined wavelength spectrum. The predetermined spectrum can have a bandwidth of at most 10 nm and can be focused at a wavelength corresponding to a maximum on a vitamin D3 phototherapy action spectrum for the predetermined energy level.

公开(公告)号：US20180056088A1

公开(公告)日：2018-03-01

申请号：US15549118

申请日：2016-02-05

申请人： BENESOL, INC.

发明人： William A. Moffat

IPC分类号： A61N5/06

CPC分类号： A61N5/0616 ,  A61N2005/0627 ,  A61N2005/064 ,  A61N2005/0641 ,  A61N2005/0661

摘要： The present disclosure is directed to systems and methods for targeted UVB phototherapy for dermatologic disorders and other indications. In one embodiment, a phototherapeutic system can include a radiation source configured to emit light. At least 75% of the light emitted by the radiation source can have wavelength with a bandwidth between 298 nm and 307 nm. The phototherapeutic system can also include a controller operably connected to the radiation source and configured to determine a dosage for a phototherapy session. Dosage can correspond to a product of the intensity of the radiation source and an exposure time of the radiation source, and may have an upper bound less than 1 minimal erythema dose (MED). Delivery of the dose of phototherapy can stimulate production of calcitriol and vitamin D3 in the user's skin and can provide an immune response to treat a dermatological disorder.

公开(公告)号：US20230347164A1

公开(公告)日：2023-11-02

申请号：US18021922

申请日：2021-08-18

申请人： BeneSol, Inc.

发明人： Gary Lauder ,  Robert Wise ,  James Wu ,  Tyson Colby ,  Brian M. Spahnie

IPC分类号： A61N5/06

CPC分类号： A61N5/0613 ,  A61N2005/0661 ,  A61N2005/0627 ,  A61N2005/0652 ,  A61N2005/0665

摘要： A home phototherapy system for producing vitamin D via skin exposure and associated methods are disclosed herein. In some embodiments, the system includes a UV-emitting device that includes a housing and a UV light assembly carried by the housing. The UV light assembly can include an array of UVB light emitters and an optical component that, together, emit phototherapeutic UV radiation from an active side of the housing to promote vitamin D production in skin (e.g., a human torso) exposed to the UVB light. The system also includes a dose controller operably coupled to the UV light assembly that can create a dosing protocol for the UV light assembly and specific to the user. The dose controller can be implemented on an application in a mobile device, within the UV-emitting device, and/or a cloud server.

公开(公告)号：US11311744B2

公开(公告)日：2022-04-26

申请号：US16954075

申请日：2018-12-13

申请人： BeneSol, Inc.

发明人： William Alexander Moffat ,  Sen Wen ,  Linda Cox Arnsdorf ,  Eben Lynn Falconer Calhoun ,  Chieh-en Wu

IPC分类号： A61N5/06 ,  G06F3/048 ,  G16H20/40 ,  G16H20/13 ,  G06N20/00 ,  A61B5/00

摘要： Dynamic dosing systems for phototherapy and associated devices, systems, and methods are disclosed herein. In some embodiments, a dynamic dosing phototherapy system can include a self-service phototherapy kiosk (“SPK”) configured to emit UV radiation, a user interface communicatively coupled to the SPK, and a dynamic dosing system communicatively coupled to the user interface and the SPK. The dynamic dosing system can determine initial, user-specific parameters specific to define a first individual phototherapy protocol, and then determine adjustments to the initial parameters and the first individual phototherapy protocol based on user inputs related to erythema response to a previous phototherapy treatment session. The SPK can deliver UV radiation to a user in accordance with the first individual phototherapy protocol and/or an adjusted, second phototherapy protocol that takes into account the user's erythema response.

公开(公告)号：US20200030628A1

公开(公告)日：2020-01-30

申请号：US16337710

申请日：2017-09-29

申请人： BENESOL, INC.

发明人： William Alexander MOFFAT ,  Keith KIRKWOOD ,  Jeff STEWART ,  Jeff ALLISON ,  Brian SHAY ,  Ned NESTOROVIC

IPC分类号： A61N5/06

摘要： A phototherapeutic system in accordance with an embodiment of the present technology includes a housing at least partially defining an irradiation zone configured to accommodate at least a portion of a human subject. The system further comprises an ultraviolet (UV) radiation source configured to direct UV radiation along a radiation path extending from the radiation source to the irradiation zone. The radiation source includes a concentrated source at which UV radiation is generated, and a collimating reflector (or lens) configured to reflect (or refract) the UV radiation and thereby increase collimation of the UV radiation. The system still further comprises a filter, a spreader, and a collimator disposed successively farther downstream from the radiation source along the radiation path. The spreader and the collimator respectively decrease and increase collimation of the UV radiation before the UV radiation reaches the subject.