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1.发明授权公开(公告)号：US11607684B2
公开(公告)日：2023-03-21
申请号：US17548591
申请日：2021-12-12
申请人： BFORCURE
发明人： Maël Le Berre
摘要： A microfluidic sample chip to test biological samples, especially for a PCR-type and/or fluorescence assay. The chip being in the shape of a hollow block having at least one chamber delimited by an upper wall, a lower wall and at least one side wall, into which a sample can be introduced for testing. The lower wall of the block is made of a material with a high thermal conductivity and the upper wall is made of a material with a low thermal conductivity. Preferably, the upper wall is preferably permeable to radiation in the visible spectrum between 400 and 700 nm. The block having at least two openings through which the sample can be introduced into at least one of the chambers and through which the air present in the chamber can be evacuated when the sample is introduced.
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2.发明申请公开(公告)号：US20190388887A1
公开(公告)日：2019-12-26
申请号：US16471500
申请日：2017-12-14
申请人： BFORCURE
发明人： MAËL LE BERRE
摘要： A microfluidic sample chip to test biological samples, especially for a PCR-type and/or fluorescence assay. The chip being in the shape of a hollow block having at least one chamber delimited by an upper wall, a lower wall and at least one side wall, into which a sample can be introduced for testing. The lower wall of the block is made of a material with a high thermal conductivity and the upper wall is made of a material with a low thermal conductivity. Preferably, the upper wall is preferably permeable to radiation in the visible spectrum between 400 and 700 nm. The block having at least two openings through which the sample can be introduced into at least one of the chambers and through which the air present in the chamber can be evacuated when the sample is introduced.
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3.发明申请公开(公告)号：US20220097049A1
公开(公告)日：2022-03-31
申请号：US17548591
申请日：2021-12-12
申请人： BFORCURE
发明人： MAËL LE BERRE
摘要： A microfluidic sample chip to test biological samples, especially for a PCR-type and/or fluorescence assay. The chip being in the shape of a hollow block having at least one chamber delimited by an upper wall, a lower wall and at least one side wall, into which a sample can be introduced for testing. The lower wall of the block is made of a material with a high thermal conductivity and the upper wall is made of a material with a low thermal conductivity. Preferably, the upper wall is preferably permeable to radiation in the visible spectrum between 400 and 700 nm. The block having at least two openings through which the sample can be introduced into at least one of the chambers and through which the air present in the chamber can be evacuated when the sample is introduced.
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公开(公告)号：US20200016593A1
公开(公告)日：2020-01-16
申请号：US16471517
申请日：2017-12-14
申请人： BFORCURE
发明人： MAËL LE BERRE , ADRIEN PLECIS , WALTER MINNELLA
摘要： A microfluidic thermalization chip, a system using such a chip and a PCR method for detecting DNA sequences. The chip contains a block of material in which a cavity is configured to contain at least one fluid. The cavity includes at least one inlet orifice and at least one outlet orifice. The inlet orifice for the fluid is connected to at least one, preferably at least two, fluid-injecting channels. Further, the chip includes at least one microfluidic channel for bypassing the cavity. The channel is connected by a first end to at least one of the fluid-injecting channels. The junction between the bypassing channel and the fluid-injecting channel is located at a distance L from the inlet orifice of the fluid-injecting channel. The distance L is preferably smaller than 2 cm.
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公开(公告)号：US20240033730A1
公开(公告)日：2024-02-01
申请号：US18039707
申请日：2021-11-29
申请人： BFORCURE
发明人： Maël LE BERRE , Claire LEBOUTEILLER , Bilal HADJI
CPC分类号： B01L3/502715 , B01L7/52 , B01L2200/025 , B01L2300/168 , B01L2300/0654 , B01L2300/0816 , B01L2300/0854 , B01L2300/18
摘要： A system for testing a microfluidic sample chip to perform PCR and/or fluorescence type testing of the biological samples. The chip having the form of a hollow block including at least one chamber delimited by an upper wall and a lower wall. The chamber receiving a sample to be tested and the chamber being associated with thermalization element and with a sensor to measure the fluorescence. The system further includes a tab, preferably opaque and/or rigid or semirigid, positioned in the continuation of, and preferably in the same plane as, the walls.
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公开(公告)号：US11198120B2
公开(公告)日：2021-12-14
申请号：US16471517
申请日：2017-12-14
申请人： BFORCURE
发明人： Maël Le Berre , Adrien Plecis , Walter Minnella
摘要： A microfluidic thermalization chip, a system using such a chip and a PCR method for detecting DNA sequences. The chip contains a block of material in which a cavity is configured to contain at least one fluid. The cavity includes at least one inlet orifice and at least one outlet orifice. The inlet orifice for the fluid is connected to at least one, preferably at least two, fluid-injecting channels. Further, the chip includes at least one microfluidic channel for bypassing the cavity. The channel is connected by a first end to at least one of the fluid-injecting channels. The junction between the bypassing channel and the fluid-injecting channel is located at a distance L from the inlet orifice of the fluid-injecting channel. The distance L is preferably smaller than 2 cm.
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