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公开(公告)号：US20230248746A1
公开(公告)日：2023-08-10
申请号：US18115020
申请日：2023-02-28
发明人： Noa RAZ , Aharon M. EYAL
IPC分类号： A61K31/00 , A61K31/015 , A61K36/185
CPC分类号： A61K31/658 , A61K31/015 , A61K36/185 , A61K2236/30
摘要： A composition of at least one cannabinoid in a specific amount, and at least one primary terpene in a specific amount, where a total terpenes to total cannabinoids weight/weight ratio in the composition is from about 0.05 to about 1.0.
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公开(公告)号：US11524042B2
公开(公告)日：2022-12-13
申请号：US15762899
申请日：2016-09-26
发明人： Aharon M. Eyal
IPC分类号： A61K36/185 , A61K31/352 , A61K31/05
摘要： Methods for the production of different cannabis product compositions. Method for the production of at least two different cannabis product compositions from a solid cannabis plant material are described including providing a solid cannabis plant material containing at least one cannabinoid and at least one terpene at cannabinoid to terpene weight/weight ratio R100; first extracting from said solid cannabis plant material a first composition comprising at least 10% but less than 90% of said cannabinoid and at least 1% of said terpene at cannabinoid to terpene weight/weight ratio R101, wherein R101 differs from R100 by at least 10%; second extracting from said solid cannabis plant material a second composition comprising at least 10% of said cannabinoid and at least 1% of said terpene at cannabinoid to terpene weight/weight ratio R102, wherein R102 differs from R101 by at least 10%; and optionally refining said first composition, said second composition, or both.
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公开(公告)号：US20220233463A1
公开(公告)日：2022-07-28
申请号：US17611583
申请日：2020-05-14
发明人： NOA RAZ , AHARON EYAL
IPC分类号： A61K31/05 , A61P29/00 , A61K31/352 , A61K31/045 , A61K31/365 , A61K31/125 , A61K31/245 , A61K31/445 , A61P23/02 , A61K31/11 , A61K31/085
摘要： Provided are methods and compositions for reducing a throat irritation caused by inhaling vapors or particles of at least one material selected from the group consisting of cannabis, cannabinoids, tobaccO, a herb or combinations thereof, the method comprising administering to a subject in need thereof at least one transient receptor potential (TRP) channel modulator prior to or simultaneously with said inhaling said vapors or particles of said at least one material. Further provided are methods and compositions comprising at least one TRP channel agonist, and/or at least one TRP channel partial agonist for treating pain-selective analgesia via TRP channels; methods for treating local pain; methods for treating migraine and symptoms thereof; and methods for treating osteoporosis and symptoms thereof.
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公开(公告)号：US20210322367A1
公开(公告)日：2021-10-21
申请号：US17359844
申请日：2021-06-28
发明人： NOA RAZ , AHARON EYAL
IPC分类号： A61K31/352 , A61K31/05 , A61K31/353 , A61P25/28 , A61P25/00 , A61P25/20 , A61P25/04 , A61P25/08 , A61P1/08 , A61K47/10 , A61K47/06 , A61K47/22
摘要： A method of treatment comprising administering to a subject in need thereof a therapeutically effective amount of a product including (i) at least one isolated or synthetic cannabinoid, where at least a fraction of said isolated or synthetic cannabinoid is obtained by a process selected from the group consisting of processing hemp, chemical synthesis, biological synthesis, isolation from a plant source, crystallization and combinations thereof, (ii) optionally, at least one other cannabinoid, (iii) at least one primary terpene, and (iv) optionally at least three secondary terpenes.
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公开(公告)号：US20230355693A1
公开(公告)日：2023-11-09
申请号：US17919753
申请日：2020-04-19
发明人： AHARON EYAL , MEIR ARIEL
IPC分类号： A61K36/185 , A24B15/18 , A24B15/22
CPC分类号： A61K36/185 , A24B15/183 , A24B15/22 , A61K2236/17 , A61K2236/13 , A61K2236/11
摘要： Provided are methods for drying and sterilizing cannabis plant material comprising providing feed cannabis plant material having a water content of M0, wherein M0 is greater than 45%; partially drying the feed cannabis plant material to form a partially dried cannabis plant material having a water content of M1, wherein M1 is in the range of between 12% wt and 40% wt; sterilizing the partially dried cannabis plant material to form sterilized partially dried cannabis plant material having a water content of M3; and when said M3 is less than 8% wt or greater than 16% wt, adjusting said M3 to provide a water content of M2, wherein said M2 is between 8% wt and 16% wt. Further provided are methods and systems for drying of cannabis plant material.
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公开(公告)号：US20230338330A1
公开(公告)日：2023-10-26
申请号：US18126443
申请日：2023-03-26
发明人： AHARON EYAL
IPC分类号： A61K31/352 , A61K9/00 , A61K9/20 , A61K31/05
CPC分类号： A61K31/352 , A61K9/0078 , A61K9/20 , A61K31/05
摘要： Homogeneous cannabis plant material compositions comprising tetrahydrocannabinol (THC) and cannabidiol (CBD) at specified concentrations, where the plant material is in the form of comminuted particles, where at least 70 wt % of the comminuted cannabis plant material is of a size greater than 0.3 and less than 4.2 millimeters, and where the composition comprises at least 1 wt % and less than 20 wt % moisture. Further provided are products comprising the compositions and methods of preparation thereof.
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公开(公告)号：US20210353638A1
公开(公告)日：2021-11-18
申请号：US17386569
申请日：2021-07-28
发明人： NOA RAZ , DANA BERNEMAN ZEITOUNI , ISO HELLER , AHARON EYAL
IPC分类号： A61K31/55 , A61K31/4045 , A61K31/4458 , A61K31/05 , A61K31/352 , A61K45/06 , A61K36/68 , A61K36/23 , A61K36/81 , A61K36/41 , A61K31/138 , A61K31/27
摘要： A terpene-enriched cannabinoid therapeutic product and methods for use thereof in treating conditions and/or symptoms associated with autism and/or autism spectrum disorder, the product including at least one cannabinoid, at least one primary terpene, and optionally at least three secondary terpenes, where the product has a therapeutic effect in treating conditions and/or symptoms associated with autism and/or autism spectrum disorder, and where said therapeutic effect is an enhanced therapeutic effect compared with that of a composition including the same cannabinoids amounts and one fifth the amount of said at least one primary terpene.
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8.发明申请公开(公告)号：US20210059978A1
公开(公告)日：2021-03-04
申请号：US17095799
申请日：2020-11-12
发明人： Noa Raz , Aharon M. Eyal
IPC分类号： A61K31/352 , A61K31/05 , A61K31/085 , A61K31/015 , A61K31/045 , A61K31/01 , A61K31/125 , A61K31/11 , A61K9/08 , A61K9/00 , A61K9/20 , A61K9/02
摘要： Provided are methods for treating conditions and/or symptoms selected from the group consisting of ulcer, viral infection, bacterial infection, fungal infection, infectious disease, and inflammation comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising at least one cannabinoid in a specific amount; at least one terpene in a specific amount, and at least 5% by weight of a non-cannabinoid, non-terpene carrier, wherein said non-cannabinoid, non-terpene carrier comprises cellulose and a weight/weight ratio of a total amount of terpenes to a total amount of cannabinoids in said composition is from about 0.1:1 to about 1:1, or wherein said non-cannabinoid, non-terpene carrier comprises less than 5% by weight cellulose and a weight/weight ratio of a total amount of terpenes to a total amount cannabinoids in said composition is about 0.05:1 to about 1:1.
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公开(公告)号：US20210046260A1
公开(公告)日：2021-02-18
申请号：US16980396
申请日：2019-03-13
发明人： Noa RAZ , Aharon M. EYAL , Carmi RAZ
摘要： An inhalation device is described, which inhalation device comprises an inlet for vapors and/or for aerosol, at least one terpene holding element configured to hold a selected terpene composition, and an outlet for vapors and/or for aerosol and wherein the device is configured to receive vapors and/or aerosol through the inlet, move the received vapors and/or aerosol through the device, infuse terpene composition into the moved vapors and/or aerosol and generate and emit terpene-enriched vapors and/or aerosol through the outlet, wherein at least one of the inlet, the holding element and the outlet is configured to limit the concentration of terpenes in the emitted terpenes-enriched vapors and/or aerosol to less than one percentage (by weight), when the moved vapors and/or aerosol is at 10 degrees Celsius and at atmospheric pressure.
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公开(公告)号：US20200253923A1
公开(公告)日：2020-08-13
申请号：US16862599
申请日：2020-04-30
发明人： Aharon EYAL
IPC分类号： A61K31/352 , A61K31/05 , A61K9/20 , A61K9/00
摘要： Provided are homogeneous cannabis plant material compositions comprising tetrahydrocannabinol (THC) and cannabidiol (CBD) at specified concentrations, wherein the plant material is in the form of comminuted particles; wherein at least 70 wt % of the comminuted cannabis plant material is of a size greater than 0.3 and less than 4.2 millimeters; and wherein the composition comprises at least 1 wt % and less than 20 wt % moisture. Further provided are products comprising the compositions and methods of preparation thereof.
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