公开(公告)号：US20130078323A1

公开(公告)日：2013-03-28

申请号：US13378932

申请日：2009-06-16

申请人： Sarang Bani ,  Anjali Pandey ,  Kiranjeet Kour ,  Prashant Singh Chauhan ,  Balkrishan Chandan ,  Neelam Sharma ,  Kuldeep Singh ,  Surrinder Koul ,  Bishan Dutt Gupta ,  Payarelal Sangwan ,  Devinder Kumar Gupta ,  Shankar Lal ,  Rajendran Marnickavasagar

发明人： Sarang Bani ,  Anjali Pandey ,  Kiranjeet Kour ,  Prashant Singh Chauhan ,  Balkrishan Chandan ,  Neelam Sharma ,  Kuldeep Singh ,  Surrinder Koul ,  Bishan Dutt Gupta ,  Payarelal Sangwan ,  Devinder Kumar Gupta ,  Shankar Lal ,  Rajendran Marnickavasagar

IPC分类号： A61K36/185

CPC分类号： A61K36/185

摘要： The present invention provides a process of extracting the leaves of Labisia pumila with water into a free flowing powder using accelerated solvent system and drying. The invention also relates to the immunopotentiating effects of the extract against stress. The extract has effects on fatigue, hypoxia time, potentiation of swimming endurance, bod weight, weight of the thymus and spleen and levels of CD244+ NK cells, CD4+ and CD8+ T cells, expression of ThI cytokines IL-2 and IFN-gamma, corticosterone, glutathione, alanine aminotransferase and lipid peroxidation levels.

摘要翻译： 本发明提供了一种使用加速溶剂体系和干燥将水分提取成自由流动粉末的Labisia pumila的叶子的方法。 本发明还涉及提取物抗压力的免疫增强作用。 提取物对疲劳，缺氧时间，游泳耐力的增强，体重，胸腺和脾的重量以及CD244 + NK细胞，CD4 +和CD8 + T细胞的水平，Th1细胞因子IL-2和IFN-γ的表达，皮质酮的影响 ，谷胱甘肽，丙氨酸氨基转移酶和脂质过氧化水平。