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公开(公告)号：US20130078323A1
公开(公告)日：2013-03-28
申请号：US13378932
申请日：2009-06-16
Applicant: Sarang Bani , Anjali Pandey , Kiranjeet Kour , Prashant Singh Chauhan , Balkrishan Chandan , Neelam Sharma , Kuldeep Singh , Surrinder Koul , Bishan Dutt Gupta , Payarelal Sangwan , Devinder Kumar Gupta , Shankar Lal , Rajendran Marnickavasagar
Inventor： Sarang Bani , Anjali Pandey , Kiranjeet Kour , Prashant Singh Chauhan , Balkrishan Chandan , Neelam Sharma , Kuldeep Singh , Surrinder Koul , Bishan Dutt Gupta , Payarelal Sangwan , Devinder Kumar Gupta , Shankar Lal , Rajendran Marnickavasagar
IPC: A61K36/185
CPC classification number: A61K36/185
Abstract: The present invention provides a process of extracting the leaves of Labisia pumila with water into a free flowing powder using accelerated solvent system and drying. The invention also relates to the immunopotentiating effects of the extract against stress. The extract has effects on fatigue, hypoxia time, potentiation of swimming endurance, bod weight, weight of the thymus and spleen and levels of CD244+ NK cells, CD4+ and CD8+ T cells, expression of ThI cytokines IL-2 and IFN-gamma, corticosterone, glutathione, alanine aminotransferase and lipid peroxidation levels.
Abstract translation: 本发明提供了一种使用加速溶剂体系和干燥将水分提取成自由流动粉末的Labisia pumila的叶子的方法。 本发明还涉及提取物抗压力的免疫增强作用。 提取物对疲劳，缺氧时间，游泳耐力的增强，体重，胸腺和脾的重量以及CD244 + NK细胞，CD4 +和CD8 + T细胞的水平，Th1细胞因子IL-2和IFN-γ的表达，皮质酮的影响 ，谷胱甘肽，丙氨酸氨基转移酶和脂质过氧化水平。
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2.发明申请Hepatocurative effect of emblica officinalis against CYP 450 bio-activation hepatotoxicity of drugs 审中-公开对药物对CYP 450生物活化肝毒性的肝胆管作用公开(公告)号：US20080138452A1
公开(公告)日：2008-06-12
申请号：US12004403
申请日：2007-12-21
Applicant: Rakesh Kamal Johri , Sheikh Tasaduq Abdullah , Kuldeep Singh , Devinder Kumar Gupta , Bal Krishan Kapahi , Dilip Manikrao Mondhe , Satinder Mohan Jain , Om Parkash Suri , Kasturi Lal Bedi , Ghulam Nabi Qazi
Inventor： Rakesh Kamal Johri , Sheikh Tasaduq Abdullah , Kuldeep Singh , Devinder Kumar Gupta , Bal Krishan Kapahi , Dilip Manikrao Mondhe , Satinder Mohan Jain , Om Parkash Suri , Kasturi Lal Bedi , Ghulam Nabi Qazi
CPC classification number: A61K36/47 , A61K2300/00
Abstract: The present invention relates to a composition useful for hepatocurative effect against CYP 450 bio-activation hepatotoxicity induced by drugs, said composition comprising an extract from Emblica officinalis and optionally pharmaceutically acceptable additives and method of treating drug induced hepatotoxicity
Abstract translation: 本发明涉及一种可用于对由药物诱导的CYP 450生物活化肝毒性的肝脏作用的组合物，所述组合物包含来自Emblica officinalis的提取物和任选的药学上可接受的添加剂和治疗药物诱导的肝毒性的方法
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3.发明授权Hepatocurative effect of emblica officinalis against CYP 450 bio-activation hepatotoxicity of drugs 有权对药物对CYP 450生物活化肝毒性的肝胆管作用公开(公告)号：US07001619B2
公开(公告)日：2006-02-21
申请号：US10106119
申请日：2002-03-27
Applicant: Rakesh Kamal Johri , Sheikh Tasaduq Abdullah , Kuldeep Singh , Devinder Kumar Gupta , Bal Krishan Kapahi , Dilip Manikrao Mondhe , Satinder Mohan Jain , Om Parkash Suri , Kasturi Lal Bedi , Ghulam Nabi Qazi
Inventor： Rakesh Kamal Johri , Sheikh Tasaduq Abdullah , Kuldeep Singh , Devinder Kumar Gupta , Bal Krishan Kapahi , Dilip Manikrao Mondhe , Satinder Mohan Jain , Om Parkash Suri , Kasturi Lal Bedi , Ghulam Nabi Qazi
CPC classification number: A61K36/47 , A61K2300/00
Abstract: The present invention relates to a composition useful for hepatocurative effect against CYP 450 bio-activation hepatotoxicity induced by drugs, said composition comprising an extract from Emblica officinalis and optionally pharmaceutically acceptable additives and method of treating drug induced hepatotoxicity.
Abstract translation: 本发明涉及一种可用于对由药物诱导的CYP 450生物活化肝毒性的肝脏作用的组合物，所述组合物包含来自Emblica officinalis的提取物和任选的药学上可接受的添加剂和治疗药物诱导的肝毒性的方法。
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