专利检索 ap:"Bhavani Miryala" 第 1 页

1.

发明申请
Lipid Substitution on Aminoglycoside Based Polymers: Plasmid Delivery, Anticancer Drug Delivery and Transgene Expression 有权
标题翻译：基于氨基糖苷的聚合物的脂质取代：质粒递送，抗癌药物递送和转基因表达

公开(公告)号：US20160279264A1

公开(公告)日：2016-09-29

申请号：US15034425

申请日：2014-11-05

申请人： Kaushal REGE , Bhavani MIRYALA , Thrimoorthy POTTA

发明人： Kaushal REGE , Bhavani MIRYALA , Thrimoorthy POTTA

IPC分类号： A61K48/00 , A61K47/48

CPC分类号： A61K48/0041 , A61K47/543 , A61K47/59 , A61K47/61 , C12N15/87

摘要： A method to form a lipid-containing aminoglycoside-based polymer, where the method includes reacting an aminoglycoside with a diepoxide to form an aminoglycoside-based polymeric material, and then reacting the aminoglycoside-based polymeric material with an acyl chloride to form the lipid-containing aminoglycoside-based polymer.

摘要翻译： 一种形成含脂质的氨基糖苷类聚合物的方法，其中所述方法包括使氨基糖苷与二环氧化物反应形成氨基糖苷类聚合物，然后使氨基糖苷类聚合物与酰氯反应形成脂质 - 含有氨基糖苷类聚合物。

2.

发明授权
Lipid substitution on aminoglycoside based polymers: plasmid delivery, anticancer drug delivery and transgene expression 有权

公开(公告)号：US09801954B2

公开(公告)日：2017-10-31

申请号：US15034425

申请日：2014-11-05

申请人： Kaushal Rege , Bhavani Miryala , Thrimoorthy Potta

发明人： Kaushal Rege , Bhavani Miryala , Thrimoorthy Potta

IPC分类号： A61K48/00 , A61K47/48 , C12N15/87

CPC分类号： A61K48/0041 , A61K47/543 , A61K47/59 , A61K47/61 , C12N15/87

摘要： A method to form a lipid-containing aminoglycoside-based polymer, where the method includes reacting an aminoglycoside with a diepoxide to form an aminoglycoside-based polymeric material, and then reacting the aminoglycoside-based polymeric material with an acyl chloride to form the lipid-containing aminoglycoside-based polymer.