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公开(公告)号:US20180371149A1
公开(公告)日:2018-12-27
申请号:US16024560
申请日:2018-06-29
申请人: Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc. , Biocant-Center of Innovation and Biotechnology
发明人: Robert S. Langer , Jeffrey M. Karp , Maria Jose Maio Nunes-Pereira , Ben Ouyang , Lino da Silva Ferreira , Debanjan Sarkar
摘要: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in sonic embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.
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公开(公告)号:US11661471B2
公开(公告)日:2023-05-30
申请号:US17573414
申请日:2022-01-11
申请人: Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc. , Biocant-Center of Innovation and Biotechnology
发明人: Robert S. Langer , Jeffrey M. Karp , Maria Jose Maio Nunes-Pereira , Ben Ouyang , Lino da Silva Ferreira , Debanjan Sarkar
CPC分类号: C08G18/4236 , A61K9/703 , A61K9/7084 , C08G18/14 , C08G18/4238 , C08G18/4283
摘要: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.
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公开(公告)号:US20210230343A1
公开(公告)日:2021-07-29
申请号:US17185528
申请日:2021-02-25
申请人: Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc. , Biocant-Center of Innovation and Biotechnology
发明人: Robert S. Langer , Jeffrey M. Karp , Maria Jose Maio Nunes-Pereira , Ben Ouyang , Lino da Silva Ferreira , Debanjan Sarkar
摘要: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.
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公开(公告)号:US11254781B2
公开(公告)日:2022-02-22
申请号:US17185528
申请日:2021-02-25
申请人: Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc. , Biocant-Center of Innovation and Biotechnology
发明人: Robert S. Langer , Jeffrey M. Karp , Maria Jose Maio Nunes-Pereira , Ben Ouyang , Lino da Silva Ferreira , Debanjan Sarkar
摘要: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.
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公开(公告)号:US10982038B2
公开(公告)日:2021-04-20
申请号:US16024560
申请日:2018-06-29
申请人: Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc. , Biocant-Center of Innovation and Biotechnology
发明人: Robert S. Langer , Jeffrey M. Karp , Maria Jose Maio Nunes-Pereira , Ben Ouyang , Lino da Silva Ferreira , Debanjan Sarkar
摘要: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B—)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.
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公开(公告)号:US20220213252A1
公开(公告)日:2022-07-07
申请号:US17573414
申请日:2022-01-11
申请人: Massachusetts Institute of Technology , The Brigham and Women's Hospital, Inc. , Biocant-Center of Innovation and Biotechnology
发明人: Robert S. Langer , Jeffrey M. Karp , Maria Jose Maio Nunes-Pereira , Ben Ouyang , Lino da Silva Ferreira , Debanjan Sarkar
摘要: Among other things, the present disclosure provides compositions and methods for an elastomeric cross-linked polyester material. Such an elastomeric cross-linked polyester material, in some embodiments, comprises a plurality of polymeric units of the general formula (-A-B-)p, wherein p is an integer greater than 1; and a plurality of urethane cross-links each of which covalently links two polymeric units to one another, which two linked polymeric unit each had at least one free hydroxyl or amino group prior to formation of the crosslink.
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