公开(公告)号：US5502386A

公开(公告)日：1996-03-26

申请号：US340100

申请日：1994-11-15

申请人： John Bourg ,  James Mitchell ,  Mark Mirotznik ,  Bradley Roth ,  Sankaran Subramanian ,  Murali Cherukuri ,  Paul G. Zablocky ,  Thomas J. Pohida ,  Paul D. Smith ,  Walter S. Friauf ,  Rolf G. Tschudin

发明人： John Bourg ,  James Mitchell ,  Mark Mirotznik ,  Bradley Roth ,  Sankaran Subramanian ,  Murali Cherukuri ,  Paul G. Zablocky ,  Thomas J. Pohida ,  Paul D. Smith ,  Walter S. Friauf ,  Rolf G. Tschudin

IPC分类号： G01R33/20 ,  A61B5/055 ,  G01N24/10 ,  G01R33/60

CPC分类号： G01R33/60

摘要： An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.

公开(公告)号：US5387867A

公开(公告)日：1995-02-07

申请号：US97811

申请日：1993-07-26

申请人： John Bourg ,  James Mitchell ,  Mark Mirotznik ,  Bradley Roth ,  Sankaran Subramanian ,  Murali Cherukuri ,  Paul G. Zablocky

发明人： John Bourg ,  James Mitchell ,  Mark Mirotznik ,  Bradley Roth ,  Sankaran Subramanian ,  Murali Cherukuri ,  Paul G. Zablocky

IPC分类号： G01R33/20 ,  A61B5/055 ,  G01N24/10 ,  G01R33/60

CPC分类号： G01R33/60

摘要： An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.

摘要翻译： EPR成像器和光谱仪包括用于产生具有不被生物样品高度吸收的RF载波频率的宽带脉冲的脉冲发生系统。 脉冲发生系统包括用于频率调制载波频率脉冲的上和下啁啾转换器，并压缩频率调制脉冲以形成高能量的宽带激励脉冲。 这种机器可以形成能够对人类患者中的自由基物质具有高度敏感性的临床成像装置的基础。