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    "> 1,4,6-androstatriene-3,17-dione (
    3.
    发明申请
    1,4,6-androstatriene-3,17-dione ("ATD") for therapeutic uses 失效
    1,4,6-雄烯三烯-3,17-二酮（“ATD”）用于治疗用途

    公开(公告)号：US20060154909A1

    公开(公告)日：2006-07-13

    申请号：US11187043

    申请日：2005-07-22

    申请人： Bruce Kneller

    发明人： Bruce Kneller

    IPC分类号： A61K31/57

    CPC分类号： A61K31/57

    摘要： A composition having modified or derivative of 1,4,6-androstatriene-3,17-dione (“ATD”) will improve the health of mammalian subjects. The improvement of health is achieved with the administration of an effective amount of the at least one modified or derivative of 1,4,6-androstatriene-3,17-dione. Particularly, health is improved for a subject suffering with a gynecomastia, and/or estrogen-dependent cancer. Also, subjects recovering from steroid misuse/abuse with treatment in accordance with the present invention. Other improvements found to occur with an administration of ATD is that growth is enhanced and/or stimulated in developing mammals, recovery is shortened in cases of severe trauma or burns, mood levels are improved, male fertility is improved, and athletic performance is improved by increasing testosterone and lean muscle mass.

    摘要翻译： 具有1,4,6-雄烯三烯-3,17-二酮（“ATD”）的修饰或衍生物的组合物将改善哺乳动物受试者的健康。 通过施用有效量的1,4,6-雄烯三烯-3,17-二酮的至少一种改性或衍生物来实现健康的改善。 特别是，对于患有男子女子乳房发育症和/或雌激素依赖性癌症的受试者而言，健康状况得到改善。 此外，根据本发明的治疗从类固醇滥用/滥用中恢复的受试者。 ATD治疗发现的其他改善是，在发展中的哺乳动物中增长和/或刺激，在严重创伤或烧伤的情况下恢复恢复，情绪水平得到改善，男性生育能力得到改善，运动性能得到改善 增加睾酮和瘦肌肉质量。

    COMPOSITIONS COMPRISING AMINO ACID BICARBONATE AND METHODS OF USE THEREOF
    4.
    发明申请
    COMPOSITIONS COMPRISING AMINO ACID BICARBONATE AND METHODS OF USE THEREOF 审中-公开
    包含氨基酸二碳酸酯的组合物及其使用方法

    公开(公告)号：US20090005320A1

    公开(公告)日：2009-01-01

    申请号：US12202979

    申请日：2008-09-02

    申请人： Bruce Kneller

    发明人： Bruce Kneller

    IPC分类号： A61K38/05 ,  A61K38/06 ,  A61K31/19

    CPC分类号： A61K38/06 ,  A23L33/175 ,  A23L33/18 ,  A23V2002/00 ,  A61K38/05 ,  A23V2200/30

    摘要： The invention relates to compositions comprising one or more ionic salts, each of said ionic salts consisting of a bicarbonate anion and a cation selected from the group consisting of an amino acid, an amino acid derivative, a di-peptide and a tri-peptide, and to methods of making and using said compositions.

    摘要翻译： 本发明涉及包含一种或多种离子盐的组合物，每种所述离子盐由碳酸氢根阴离子和选自氨基酸，氨基酸衍生物，二肽和三肽的阳离子组成， 以及制备和使用所述组合物的方法。

    Modified aromatase inhibitors having improved bioavailability
    6.
    发明申请
    Modified aromatase inhibitors having improved bioavailability 审中-公开
    具有改善的生物利用度的改性芳香酶抑制剂

    公开(公告)号：US20050203074A1

    公开(公告)日：2005-09-15

    申请号：US11079868

    申请日：2005-03-12

    申请人： Bruce Kneller

    发明人： Bruce Kneller

    IPC分类号： A61K31/57

    CPC分类号： A61K31/568 ,  A61K31/5685

    摘要： The present invention relates to the modification of 3-beta-hydroxyandrost-4-ene-6,17-dione (“3-OHAT”) and its metabolites/derivatives at either the 3rd or 17th carbon or 3rd and 17th carbons with various ethers and/or esters and to the modification of 3-beta-hydroxyandrost-4-ene-6,17-dione (“3-OHAT”) and its metabolites/derivatives at carbon 6 with a methyl, methoxy, methylene, hydroxymethylene or acetoxy functional group to improve and increase the oral bioavailability and/or plasma half life and/or efficacy in mammals.

    摘要翻译： 本发明涉及3-β-羟基雄甾-4-烯-6,17-二酮（“3-OHAT”）及其代谢物/衍生物在3'或17“ 具有各种醚和/或酯的碳原子或第三和第十七个和第十七个碳以及3-β-羟基雄甾-4-烯的改性 -6,17-二酮（“3-OHAT”）及其在碳6处的代谢物/衍生物与甲基，甲氧基，亚甲基，羟基亚甲基或乙酰氧基官能团，以改善和增加口服生物利用度和/或血浆半衰期和/或 哺乳动物的功效。

    Palatinose for enhancing dietary supplement and pharmaceutical delivery
    8.
    发明申请
    Palatinose for enhancing dietary supplement and pharmaceutical delivery 有权
    Palatinose用于增强膳食补充剂和药物递送

    公开(公告)号：US20060153899A1

    公开(公告)日：2006-07-13

    申请号：US11385137

    申请日：2006-03-20

    申请人： Bruce Kneller

    发明人： Bruce Kneller

    IPC分类号： A61K47/00

    CPC分类号： A61K31/7016 ,  A61K9/0019 ,  A61K31/122 ,  A61K31/197 ,  A61K31/566 ,  A61K31/70 ,  A61K31/7076 ,  A61K33/00 ,  A61K38/05 ,  A61K45/06

    摘要： The present invention is directed to a dietary supplement comprising palatinose or a derivative thereof. The dietary supplement may be a nutritional product, a sports performance product, a weight loss product or a meal replacement product. The present invention is also directed to a method of increasing the absorption of a compound into the bloodstream, cells and tissue comprising administering palatinose, or a derivative thereof, in combination with the compound. The present invention also relates to a diluent for parenteral compounds. The diluent comprises palatinose or a derivative thereof. Another aspect of the present invention is directed to a method of decreasing the recovery time to pre-performance levels of total adenosine triphosphate (ATP) levels in a mammal comprising administering palatinose, or a derivative thereof, to the mammal. The present invention is further directed to a method of supplying a compound to a diabetic patient, burn victim patient or trauma victim patient. The method comprises administering palatinose, or a derivative thereof, in combination with the compound.

    摘要翻译： 本发明涉及包含帕拉金糖或其衍生物的膳食补充剂。 膳食补充剂可以是营养产品，运动性能产品，减肥产品或膳食替代产品。 本发明还涉及增加化合物进入血流，细胞和组织的吸收的方法，包括与化合物组合施用帕拉金糖或其衍生物。 本发明还涉及一种用于胃肠外化合物的稀释剂。 稀释剂包括帕拉金糖或其衍生物。 本发明的另一方面涉及一种减少在哺乳动物中将总胆固醇三磷酸（ATP）水平恢复至预期水平的恢复时间的方法，其包括对哺乳动物施用帕拉金糖或其衍生物。 本发明还涉及向糖尿病患者，烧伤患者或创伤受害者患者提供化合物的方法。 该方法包括与化合物组合施用帕拉金糖或其衍生物。