Process for preparing 5,6-dihydroxyindole
    4.
    发明授权
    Process for preparing 5,6-dihydroxyindole 失效
    制备5,6-二羟基吲哚的方法

    公开(公告)号:US4595765A

    公开(公告)日:1986-06-17

    申请号:US788510

    申请日:1985-10-18

    Inventor: Bryan P. Murphy

    CPC classification number: C07D209/08

    Abstract: 5,6-Dihydroxyindole is prepared by the catalytic reductive cyclization of 4,5-dihydroxy-2,.beta.-dinitrostyrene in a single step using hydrogen with a palladium, platinum or rhodium catalyst in a polar hydroxylic reaction system. No reaction byproducts or only a single reaction byproduct are produced. The 4,5-dihydroxy-2,.beta.-dinitrostyrene intermediate can be prepared by the chemoselective debenzylation of 4,5-dibenzyloxy-2,.beta.-dinitrostyrene using trifluoroacetic acid. 5,6-Dihydroxyindole is a useful component in hair dye formulations and as an intermediate in the synthesis of melanin.

    Abstract translation: 通过在极性羟基反应体系中使用氢气与钯,铂或铑催化剂在一个步骤中通过催化还原环化4,5-二羟基-2β-二硝基苯乙烯制备5,6-二羟基吲哚。 不产生反应副产物或仅产生单一反应副产物。 4,5-二羟基-2,β-二硝基苯乙烯中间体可以通过使用三氟乙酸的4,5-二苄氧基-2,β-二硝基苯乙烯的化学选择性脱苄基化来制备。 5,6-二羟基吲哚是染发剂制剂中的有用成分,也是合成黑色素的中间体。

    Hair dyeing process and compositons package
    7.
    发明授权
    Hair dyeing process and compositons package 失效
    染发工艺及组合包装

    公开(公告)号:US5173085A

    公开(公告)日:1992-12-22

    申请号:US649132

    申请日:1991-01-29

    CPC classification number: A61Q5/10 A61K8/19 A61K8/492

    Abstract: A hair dyeing process which comprises of steps of contacting the hair to be dyed with an aqueous solution of a metal salt that promotes melanogenses in air. Before or after the aforementioned step contacting the hair with a solution of 5,6-dihydroxyindole, rinsing the hair between the two contacting steps, maintaining the contact with the second-used solution until a desired darker color is obtained, rinsing or shampooing the hair, then contacting the hair with a solution of hydrogen peroxide until the desired color shade is obtained, and then again rinsing the hair.

    Abstract translation: 一种染发方法,其包括使被染色的毛发与促进空气中的黑质素的金属盐的水溶液接触的步骤。 在上述步骤之前或之后,将毛发与5,6-二羟基吲哚的溶液接触,在两个接触步骤之间冲洗毛发,保持与第二次使用的溶液的接触直至获得所需的较暗颜色,漂洗或洗发头发 然后将毛发与过氧化氢溶液接触直至获得所需的色调,然后再次冲洗头发。

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