公开(公告)号：US06649755B1

公开(公告)日：2003-11-18

申请号：US10111636

申请日：2002-04-26

申请人： Chung Il Hong ,  Kyung Hwan Kim ,  Byoung Taik Choi ,  Gang Sun Choi ,  Yong Rack Choi

发明人： Chung Il Hong ,  Kyung Hwan Kim ,  Byoung Taik Choi ,  Gang Sun Choi ,  Yong Rack Choi

IPC分类号： C07H506

CPC分类号： C07H15/203

摘要： Disclosed herein is a process for preparing highly pure acarbose of formula (I) useful as medicine for the treatment of diabetes. The disclosed process comprises prepurifying an acarbose-containing solution using a synthetic adsorbent to produce a prepurified acarbose having an acarbose content of a predetermined level or more; and contacting the prepurified acarbose with a monodispersed, strongly acid cation exchanger, in one step, to absorb acarbose.

摘要翻译： 本文公开了一种制备用作治疗糖尿病药物的式（I）的高纯度阿卡波糖的方法。 所公开的方法包括使用合成吸附剂对含阿卡波糖的溶液进行预净化以产生具有预定水平或更高水平的阿卡波糖含量的预纯化阿卡波糖; 并在一个步骤中将预纯化的阿卡波糖与单分散的强酸阳离子交换剂接触以吸收阿卡波糖。