公开(公告)号：US20080031811A1

公开(公告)日：2008-02-07

申请号：US11575170

申请日：2005-09-12

申请人： Jei-Man Ryu ,  Yu-Eun Kim ,  Seung-Kyoo Seong ,  Dong-Hyuk Shin ,  Byung-Ho Cho ,  Young-Jun Song ,  Kyung-Bae Park ,  Byung-Chul Shin

发明人： Jei-Man Ryu ,  Yu-Eun Kim ,  Seung-Kyoo Seong ,  Dong-Hyuk Shin ,  Byung-Ho Cho ,  Young-Jun Song ,  Kyung-Bae Park ,  Byung-Chul Shin

IPC分类号： A61K51/12 ,  A61M36/14

CPC分类号： A61K51/1279 ,  C08J5/18 ,  C08J2375/04 ,  C08K3/16 ,  C08K3/28

摘要： The present invention relates to a method for preparing a radioactive film for local radioactive treatment. More particularly, the present invention relates to a method for preparing a radioactive film comprising the steps of; dissolving 0.1˜14.5 weight % of a stable nuclide and 13˜32.5 weight % of a film-forming base for the total amount of a solvent in the solvent; applying a stable nuclide solution on a release paper by a coater and drying; and irradiating a stable nuclide film with neutrons in a nuclear reactor. A method for preparing a radioactive film according to the present invention provides a radioactive film having a uniform distribution of radionuclides and an even thickness. Therefore, the therapeutic efficacy of the radioactive film for selective treatment of a lesion may be maximized by attaching the radioactive film on a patient's skin or a mucous membrane and by direct radioactive radiation.

摘要翻译： 本发明涉及一种用于局部放射性处理的放射性膜的制备方法。 更具体地，本发明涉及一种制备放射性膜的方法，包括以下步骤： 将0.1〜14.5重量％的稳定核素和13〜32.5重量％的成膜基质溶解在溶剂中的溶剂的总量; 通过涂布机将稳定的核素溶液施加在剥离纸上并干燥; 并在核反应堆中用中子照射稳定的核素膜。 根据本发明的制备放射性膜的方法提供了具有均匀分布的放射性核素的均匀厚度的放射性膜。 因此，通过将放射性膜附着在患者的皮肤或粘膜上以及通过直接的放射性辐射，用于选择性治疗病变的放射性膜的治疗功效可以最大化。