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公开(公告)号：US12202816B2
公开(公告)日：2025-01-21
申请号：US17278489
申请日：2019-09-27
Applicant: CALLIDITAS THERAPEUTICS SUISSE SA
Inventor： Peter Machin , Mark Chambers , Alastair Hodges , Andrew Sharpe , Grant Wishart , Benjamin Perry , Sylvain Celanire , Freddy Heitz
IPC: C07D401/14 , A61K45/06 , A61P1/16 , C07D405/14 , C07D417/14 , C07D491/107 , C07D491/20 , C07D498/04
Abstract: Disclosed herein are new compounds, pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
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公开(公告)号：US20240358687A1
公开(公告)日：2024-10-31
申请号：US18651929
申请日：2024-05-01
Inventor： Philippe WIESEL , Freddy HEITZ , Gareth THOMAS , Christopher HANLEY , Kristy FORD
IPC: A61K31/437 , A61K31/4025 , A61K31/5377 , A61K35/17 , A61K38/19 , A61K39/00 , A61K39/245 , A61K39/395 , A61P35/00
CPC classification number: A61K31/437 , A61K31/4025 , A61K31/5377 , A61K35/17 , A61K38/191 , A61K39/245 , A61K39/3955 , A61P35/00 , A61K2039/505 , A61K2039/507
Abstract: The present invention is related to compounds, methods, compositions and uses that are able to restore responsiveness to immunotherapy, in particular immune check point inhibitors or anti-cancer vaccine or to anti-angiogenesis treatment.
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公开(公告)号：US12011436B2
公开(公告)日：2024-06-18
申请号：US16760910
申请日：2018-11-01
Inventor： Philippe Wiesel , Freddy Heitz , Gareth Thomas , Christopher Hanley , Kirsty Ford
IPC: A61K31/437 , A61K31/4025 , A61K31/5377 , A61K35/17 , A61K38/19 , A61K39/00 , A61K39/245 , A61K39/395 , A61P35/00
CPC classification number: A61K31/437 , A61K31/4025 , A61K31/5377 , A61K35/17 , A61K38/191 , A61K39/245 , A61K39/3955 , A61P35/00 , A61K2039/505 , A61K2039/507
Abstract: The present invention is related to compounds, methods, compositions and uses that are able to restore responsiveness to immunotherapy, in particular immune check point inhibitors or anti-cancer vaccine or to anti-angiogenesis treatment.
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