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公开(公告)号:US12011436B2
公开(公告)日:2024-06-18
申请号:US16760910
申请日:2018-11-01
IPC分类号: A61K31/437 , A61K31/4025 , A61K31/5377 , A61K35/17 , A61K38/19 , A61K39/00 , A61K39/245 , A61K39/395 , A61P35/00
CPC分类号: A61K31/437 , A61K31/4025 , A61K31/5377 , A61K35/17 , A61K38/191 , A61K39/245 , A61K39/3955 , A61P35/00 , A61K2039/505 , A61K2039/507
摘要: The present invention is related to compounds, methods, compositions and uses that are able to restore responsiveness to immunotherapy, in particular immune check point inhibitors or anti-cancer vaccine or to anti-angiogenesis treatment.