公开(公告)号：US20200268914A1

公开(公告)日：2020-08-27

申请号：US16870776

申请日：2020-05-08

Applicant: CURASIGHT APS

Inventor： Andreas KJAER ,  Morten PERSSON ,  Jacob MADSEN

IPC: A61K51/08 ,  A61K38/08

Abstract: There is provided a positron-emitting radionuclide labelled peptide for non-invasive PET imaging of the Urokinase-type Plasminogen Activator Receptor (uPAR) in humans. More specifically the invention relates to human uPAR PET imaging of any solid cancer disease for diagnosis, staging, treatment monitoring and especially as an imaging biomarker for predicting prognosis, progression and recurrence.

公开(公告)号：US20160263260A1

公开(公告)日：2016-09-15

申请号：US14649113

申请日：2013-11-29

Applicant: Curasight ApS

Inventor： Andreas KJAER ,  Morten PERSSON ,  Jacob MADSEN

IPC: A61K51/08

CPC classification number: A61K51/088 ,  A61K38/08 ,  A61K51/08 ,  A61K51/083

Abstract: There is provided a positron-emitting radionuclide labelled peptide for non-invasive PET imaging of the Urokinase-type Plasminogen Activator Receptor (uPAR) in humans. More specifically the invention relates to human uPAR PET imaging of any solid cancer disease for diagnosis, staging, treatment monitoring and especially as an imaging biomarker for predicting prognosis, progression and recurrence.

Abstract translation: 提供了一种用于人类尿激酶型纤溶酶原激活受体（uPAR）的非侵入性PET成像的正电子发射放射性核素标记肽。 更具体地，本发明涉及用于诊断，分期，治疗监测的任何固体癌症疾病的人类uPAR PET成像，特别是用于预测预后，进展和复发的成像生物标志物。

公开(公告)号：US20180193495A1

公开(公告)日：2018-07-12

申请号：US15832371

申请日：2017-12-05

Applicant: CURASIGHT APS

Inventor： Andreas Kjaer ,  Morten Persson ,  Jacob Madsen

IPC: A61K51/08 ,  A61K38/08

CPC classification number: A61K51/088 ,  A61K38/08 ,  A61K51/08 ,  A61K51/083

Abstract: There is provided a positron-emitting radionuclide labelled peptide for non-invasive PET imaging of the Urokinase-type Plasminogen Activator Receptor (uPAR) in humans. More specifically the invention relates to human uPAR PET imaging of any solid cancer disease for diagnosis, staging, treatment monitoring and especially as an imaging biomarker for predicting prognosis, progression and recurrence.

公开(公告)号：US09884131B2

公开(公告)日：2018-02-06

申请号：US14649113

申请日：2013-11-29

Applicant: Curasight ApS

Inventor： Andreas Kjaer ,  Morten Persson ,  Jacob Madsen

IPC: A61K51/00 ,  A61M36/14 ,  A61K51/08 ,  A61K38/08

CPC classification number: A61K51/088 ,  A61K38/08 ,  A61K51/08 ,  A61K51/083

Abstract: There is provided a positron-emitting radionuclide labelled peptide for non-invasive PET imaging of the Urokinase-type Plasminogen Activator Receptor (uPAR) in humans. More specifically the invention relates to human uPAR PET imaging of any solid cancer disease for diagnosis, staging, treatment monitoring and especially as an imaging biomarker for predicting prognosis, progression and recurrence.