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公开(公告)号：US20070077239A1
公开(公告)日：2007-04-05
申请号：US11514578
申请日：2006-09-01
CPC分类号： A61K48/0008 , A61K38/00 , A61K47/62 , A61K47/66 , B82Y5/00 , C12N9/0065
摘要： The present invention is directed to compositions based on myeloperoxidase amino acid sequence which may be used as therapeutic agents or as delivery vehicles for the delivery of other therapeutic agents.
摘要翻译： 本发明涉及可用作治疗剂或作为递送其它治疗剂的递送载体的基于髓过氧化物酶氨基酸序列的组合物。
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公开(公告)号：US06204054B1
公开(公告)日：2001-03-20
申请号：US09043412
申请日：1998-06-25
IPC分类号： C12N506
CPC分类号： C07K14/705 , A61K38/00 , A61K47/62 , A61K47/6425 , A61K47/6849
摘要： Transcytosis of a physiologically-active agent that exerts its action following passage across endothelia, epithelia or mesothelia containing the GP60 receptor is enhanced by formulation with or conjugation to a transcytosis enhancer or vehicle selected from albumin and fragments thereof, anti-GP60 antibody and fragments thereof, GP60 peptide fragments, and PDI (protein disulphide isomerase) and fragments thereof.
摘要翻译： 通过与含有GP60受体的内皮，上皮或间皮穿过之间发挥其作用的生理活性剂的细胞因子通过与选择白蛋白及其片段，抗GP60抗体及其片段的转细胞增生剂或载体配制或缀合而增强 ，GP60肽片段和PDI（蛋白质二硫化物异构酶）及其片段。
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公开(公告)号：US07429563B2
公开(公告)日：2008-09-30
申请号：US11514578
申请日：2006-09-01
CPC分类号： A61K48/0008 , A61K38/00 , A61K47/62 , A61K47/66 , B82Y5/00 , C12N9/0065
摘要： The present invention is directed to compositions based on myeloperoxidase amino acid sequence which may be used as therapeutic agents or as delivery vehicles for the delivery of other therapeutic agents.
摘要翻译： 本发明涉及可用作治疗剂或作为递送其它治疗剂的递送载体的基于髓过氧化物酶氨基酸序列的组合物。
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