公开(公告)号：US20080081932A1

公开(公告)日：2008-04-03

申请号：US11857248

申请日：2007-09-18

Applicant: Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

Inventor： Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

IPC: C07C35/21

CPC classification number: C07C403/24 ,  A23L5/44 ,  A23L33/10 ,  C07C2601/16 ,  C09B61/00 ,  C09B67/0025 ,  C09B67/0096

Abstract: This invention has disclosed a method for preparation of food-grade zeaxanthin through chemical isomerizaton reaction from lutein. The technical issues to be solved in this invention are quite low product yield obtained with existing methods, need of purification treatment process, and inadaptability to industrialized production. The technical schemes of this invention are: a. Mix xanthophyll crystal or its fatty acid ester with food-grade glycol or propylene glycol, for full dissolution under 60-90° C. temperature. Add organic alkali into the mixed liquor acquired from step 1, for isomerization reaction to take place under inertial environment. c. Dilute the reaction solution gained from step b with the mixed solution of deionized water and ethanol, and separate the obtained crystal with conventional separating method. d. Vacuum dries the acquired crystal from step c, to get the zeaxanthin crystal. Glycol or propylene glycol is used in this invention for isomerization reaction under inertial environment after it has fully dissolved raw material under proper temperature. The product yield is reachable to more than 60%, very adaptable to industrialized product, without the need for further purification treatment.

Abstract translation: 本发明公开了通过叶黄素化学异构化反应制备食品级玉米黄质的方法。 本发明要解决的技术问题是用现有方法获得的产品产率相当低，需要净化处理工艺，以及对工业化生产的适应性。 本发明的技术方案是：a。 将叶黄素晶体或其脂肪酸酯与食品级二醇或丙二醇混合，在60-90℃的温度下完全溶解。 将有机碱添加到从步骤1获得的混合液中，以在惯性环境下进行异构化反应。 C。 用去离子水和乙醇的混合溶液稀释从步骤b获得的反应溶液，并用常规分离方法分离得到的晶体。 d。 真空干燥步骤c获得的晶体，得到玉米黄质晶体。 乙二醇或丙二醇在本发明中在适当温度下完全溶解原料之后，在惯性环境下用于异构化反应。 产品产量可达60％以上，非常适用于工业化产品，无需进一步净化处理。

公开(公告)号：US07485738B2

公开(公告)日：2009-02-03

申请号：US11857248

申请日：2007-09-18

Applicant: Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

Inventor： Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

IPC: C07C51/353

CPC classification number: C07C403/24 ,  A23L5/44 ,  A23L33/10 ,  C07C2601/16 ,  C09B61/00 ,  C09B67/0025 ,  C09B67/0096

Abstract: This invention has disclosed a method for preparation of food-grade zeaxanthin through chemical isomerizaton reaction from lutein. The technical issues to be solved in this invention are quite low product yield obtained with existing methods, need of purification treatment process, and inadaptability to industrialized production. The technical schemes of this invention are: a. Mix xanthophyll crystal or its fatty acid ester with food-grade glycol or propylene glycol, for full dissolution under 60-90° C. temperature. Add organic alkali into the mixed liquor acquired from step 1, for isomerization reaction to take place under inertial environment. c. Dilute the reaction solution gained from step b with the mixed solution of deionized water and ethanol, and separate the obtained crystal with conventional separating method. d. Vacuum dries the acquired crystal from step c, to get the zeaxanthin crystal. Glycol or propylene glycol is used in this invention for isomerization reaction under inertial environment after it has fully dissolved raw material under proper temperature. The product yield is reachable to more than 60%, very adaptable to industrialized product, without the need for further purification treatment.

Abstract translation: 本发明公开了通过叶黄素化学异构化反应制备食品级玉米黄质的方法。 本发明要解决的技术问题是用现有方法获得的产品产率相当低，需要净化处理工艺，以及对工业化生产的适应性。 本发明的技术方案是：a。 将叶黄素晶体或其脂肪酸酯与食品级二醇或丙二醇混合，在60-90℃的温度下完全溶解。 将有机碱添加到从步骤1获得的混合液中，以在惯性环境下进行异构化反应。 C。 用去离子水和乙醇的混合溶液稀释从步骤b获得的反应溶液，并用常规分离方法分离得到的晶体。 d。 真空干燥步骤c获得的晶体，得到玉米黄质晶体。 乙二醇或丙二醇在本发明中在适当温度下完全溶解原料之后，在惯性环境下用于异构化反应。 产品产量可达60％以上，非常适用于工业化产品，无需进一步净化处理。