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1.(1,2,4)TRIAZOLO[4,3-A]QUINOXALINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES 有权
标题翻译: (1,2,4)三唑并[4,3-A]喹唑啉衍生物作为磷酸二酯的抑制剂公开(公告)号:US20120302564A1
公开(公告)日:2012-11-29
申请号:US13361002
申请日:2012-01-30
申请人: Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
发明人: Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
IPC分类号: A61K31/4985 , A61K31/5377 , A61P25/00 , A61P25/28 , A61P3/10 , A61P25/18 , A61P25/08 , A61P15/00 , C07D487/04 , A61P3/04
CPC分类号: C07D487/04 , A61K31/519 , A61K45/06 , A61K2300/00
摘要: The invention relates to (1,2,4)triazolo[4,3-a]quinoxaline derivatives which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases.
摘要翻译: 本发明涉及作为治疗中枢神经系统疾病的磷酸二酯酶2和/或10的抑制剂的(1,2,4)三唑并[4,3-a]喹喔啉衍生物。
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2.(1,2,4)triazolo[4,3-A]quinoxaline derivatives as inhibitors of phosphodiesterases 有权
标题翻译: (1,2,4)三唑并[4,3-A]喹喔啉衍生物作为磷酸二酯酶的抑制剂公开(公告)号:US09540379B2
公开(公告)日:2017-01-10
申请号:US13361002
申请日:2012-01-30
申请人: Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
发明人: Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
IPC分类号: A61K31/535 , C07D487/04 , A61K31/519 , A61K45/06
CPC分类号: C07D487/04 , A61K31/519 , A61K45/06 , A61K2300/00
摘要: The invention relates to (1,2,4)triazolo[4,3-a]quinoxaline derivatives which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases.
摘要翻译: 本发明涉及作为治疗中枢神经系统疾病的磷酸二酯酶2和/或10的抑制剂的(1,2,4)三唑并[4,3-a]喹喔啉衍生物。
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3.Substituted pyrido[3,2-E][1,2,4]-triazolo[4,3-A]pyrazines for the treatment of central nervous system disorders 有权
标题翻译: 取代的吡啶并[3,2-E] [1,2,4] - 三唑并[4,3-A]吡嗪用于治疗中枢神经系统疾病公开(公告)号:US09085584B2
公开(公告)日:2015-07-21
申请号:US13951531
申请日:2013-07-26
申请人: Riccardo Giovannini , Barbara Bertani , Sara Frattini , Giustino Di Antonio , Hans-Joachim Lankau , Hans Stange , Christian Grunwald , Norbert Höfgen , Barbara Langen , Ute Egerland
发明人: Riccardo Giovannini , Barbara Bertani , Sara Frattini , Giustino Di Antonio , Hans-Joachim Lankau , Hans Stange , Christian Grunwald , Norbert Höfgen , Barbara Langen , Ute Egerland
IPC分类号: A61K31/4985 , C07D487/14 , C07D471/14
CPC分类号: C07D487/14 , C07D471/14
摘要: The compounds are of the class of pyrido[3,2-e][1,2,4]-tiazolo[4,3-a]pyrazines, useful in the treatment of central nervous system disorders. A species illustrative of members of the class is the following:
摘要翻译: 这些化合物是可用于治疗中枢神经系统疾病的吡啶并[3,2-e] [1,2,4] - 噻唑并[4,3-a]吡嗪类。 课程成员的种类说明如下:
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