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![(1,2,4)TRIAZOLO[4,3-A]QUINOXALINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES](/abs-image/US/2012/11/29/US20120302564A1/abs.jpg.150x150.jpg)
1.发明申请(1,2,4)TRIAZOLO[4,3-A]QUINOXALINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES 有权（1,2,4）三唑并[4,3-A]喹唑啉衍生物作为磷酸二酯的抑制剂公开(公告)号：US20120302564A1
公开(公告)日：2012-11-29
申请号：US13361002
申请日：2012-01-30
申请人： Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
发明人： Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
IPC分类号： A61K31/4985 , A61K31/5377 , A61P25/00 , A61P25/28 , A61P3/10 , A61P25/18 , A61P25/08 , A61P15/00 , C07D487/04 , A61P3/04
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , A61K2300/00
摘要： The invention relates to (1,2,4)triazolo[4,3-a]quinoxaline derivatives which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases.
摘要翻译： 本发明涉及作为治疗中枢神经系统疾病的磷酸二酯酶2和/或10的抑制剂的（1,2,4）三唑并[4,3-a]喹喔啉衍生物。
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![(1,2,4)triazolo[4,3-A]quinoxaline derivatives as inhibitors of phosphodiesterases](/abs-image/US/2017/01/10/US09540379B2/abs.jpg.150x150.jpg)
2.发明授权(1,2,4)triazolo[4,3-A]quinoxaline derivatives as inhibitors of phosphodiesterases 有权（1,2,4）三唑并[4,3-A]喹喔啉衍生物作为磷酸二酯酶的抑制剂公开(公告)号：US09540379B2
公开(公告)日：2017-01-10
申请号：US13361002
申请日：2012-01-30
申请人： Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
发明人： Hans-Joachim Lankau , Barbara Langen , Christian Grunwald , Norbert Hoefgen , Hans Stange , Rita Dost , Ure Egerland
IPC分类号： A61K31/535 , C07D487/04 , A61K31/519 , A61K45/06
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , A61K2300/00
摘要： The invention relates to (1,2,4)triazolo[4,3-a]quinoxaline derivatives which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases.
摘要翻译： 本发明涉及作为治疗中枢神经系统疾病的磷酸二酯酶2和/或10的抑制剂的（1,2,4）三唑并[4,3-a]喹喔啉衍生物。
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公开(公告)号：US20100120762A1
公开(公告)日：2010-05-13
申请号：US12614139
申请日：2009-11-06
申请人： Hans Stange , Barbara Langen , Ute Egerland , Norbert Hoefgen , Martina Priebs , Michael S. Malamas , James Joseph Erdei , Yike Ni
发明人： Hans Stange , Barbara Langen , Ute Egerland , Norbert Hoefgen , Martina Priebs , Michael S. Malamas , James Joseph Erdei , Yike Ni
IPC分类号： A61K31/5377 , C07D487/14 , A61K31/53 , C07D413/14 , A61P25/00 , A61P3/10 , A61P3/04 , A61P29/00 , A61P11/00 , A61P1/16 , A61P13/12 , A61P35/00 , A61P9/00
CPC分类号： C07D471/14 , C07D519/00
摘要： The invention relates to triazine derivatives of formula (I): which are inhibitors of phosphodiesterase 2 or 10, useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type 2 diabetes, metabolic syndrome, glucose intolerance, and pain.
摘要翻译： 本发明涉及式（I）的三嗪衍生物：其是磷酸二酯酶2或10的抑制剂，其可用于治疗中枢神经系统疾病如精神病，并且还用于治疗例如肥胖，2型糖尿病，代谢综合征，葡萄糖耐受不良 ，和痛苦。
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![IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES](/abs-image/US/2010/05/13/US20100120763A1/abs.jpg.150x150.jpg)
4.发明申请IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES 审中-公开咪唑并[5,1-C] [1,2,4]苯并噻嗪衍生物作为磷酸二酯的抑制剂公开(公告)号：US20100120763A1
公开(公告)日：2010-05-13
申请号：US12614146
申请日：2009-11-06
申请人： Hans Stange , Barbara Langen , Ute Egerland , Norbert Hoefgen , Martina Priebs , Michael S. Malamas , James Joseph Erdei , Yike Ni
发明人： Hans Stange , Barbara Langen , Ute Egerland , Norbert Hoefgen , Martina Priebs , Michael S. Malamas , James Joseph Erdei , Yike Ni
IPC分类号： A61K31/5377 , C07D487/04 , A61K31/53
CPC分类号： C07D487/04
摘要： The invention relates to imidazo[5,1-c][1,2,4]benzotriazine derivatives of formula I: which are inhibitors of phosphodiesterase 2 or 10 useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type 2 diabetes, metabolic syndrome, glucose intolerance, and pain.
摘要翻译： 本发明涉及式I的咪唑并[5,1-c] [1,2,4]苯并三嗪衍生物：其是可用于治疗中枢神经系统疾病如精神病的磷酸二酯酶2或10的抑制剂，也用于治疗例如 ，肥胖症，2型糖尿病，代谢综合征，葡萄糖不耐受和疼痛。
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