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1.
公开(公告)号:US20100056766A1
公开(公告)日:2010-03-04
申请号:US12199047
申请日:2008-08-27
申请人: Marcela De Leon Gatti , Yingqing Huang , David K. Schisla , Lou-Hwa J. Sheu , Christopher A. Tomas
发明人: Marcela De Leon Gatti , Yingqing Huang , David K. Schisla , Lou-Hwa J. Sheu , Christopher A. Tomas
IPC分类号: C07K1/00
CPC分类号: C07K1/16 , A61K2039/505 , C07G11/00 , C07H17/08 , C07K1/34
摘要: A method for separating a biological conjugate from an aggregate. The molecular weight of the biological conjugate ranges from about 10 kDa to about 1000 kDa. In one embodiment, the method comprises the steps of: (e) providing a mixture comprising the biological conjugate and the aggregate, wherein the biological conjugate has a molecular weight of from about 10 kDa to about 1000 kDa; (f) providing a chromatography column containing a gel, wherein the gel comprises at least one polysaccharide; (g) introducing the mixture of step (a) into the chromatography column; (h) recovering the biological conjugate from the column.
摘要翻译: 从聚集体中分离生物缀合物的方法。 生物结合物的分子量范围为约10kDa至约1000kDa。 在一个实施方案中,该方法包括以下步骤:(e)提供包含生物缀合物和聚集体的混合物,其中生物缀合物具有约10kDa至约1000kDa的分子量; (f)提供含有凝胶的色谱柱,其中所述凝胶包含至少一种多糖; (g)将步骤(a)的混合物引入色谱柱; (h)从柱中回收生物缀合物。
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公开(公告)号:US06960465B1
公开(公告)日:2005-11-01
申请号:US10186335
申请日:2002-06-27
CPC分类号: C07K14/33
摘要: Recombinant microorganisms and related methods of use to enhance tolerance to toxic substances. In particular, such microorganisms and methods can be used to increase solvent production.
摘要翻译: 重组微生物及相关使用方法,增强对有毒物质的耐受性。 特别地,这种微生物和方法可用于增加溶剂的生产。
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