公开(公告)号：US20080241569A1

公开(公告)日：2008-10-02

申请号：US11694293

申请日：2007-03-30

申请人： Haoyu Qin ,  Jingwu Zhang ,  Claire E. Dentinger ,  Lei Sun ,  Xing Su

发明人： Haoyu Qin ,  Jingwu Zhang ,  Claire E. Dentinger ,  Lei Sun ,  Xing Su

IPC分类号： B32B5/16

CPC分类号： G01N21/658 ,  B82Y15/00 ,  B82Y30/00 ,  Y10T428/12028 ,  Y10T428/2991

摘要： Embodiments of the present invention provide methods for coating nanoparticles with polymeric coatings and nanoparticles that are coated with polymeric coatings. The polymeric coatings typically comprise two or more layers wherein the first layer has a charge that is opposite to that of the second layer. In further embodiments, the nanoparticles that can act as labels or reporters are coated with polymeric coatings. Optionally, these reporter or label nanoparticles may be Raman-active, such that they provide a distinctive Raman signature upon excitation with electromagnetic radiation.

摘要翻译： 本发明的实施方案提供了用聚合物涂层和纳米颗粒涂覆聚合物涂层的方法。 聚合物涂层通常包含两层或更多层，其中第一层具有与第二层相反的电荷。 在另外的实施方案中，可以用作标记或报告物的纳米颗粒涂覆有聚合物涂层。 任选地，这些报告物或标记纳米颗粒可以是拉曼活性的，使得它们在用电磁辐射激发时提供独特的拉曼特征。