公开(公告)号：US20120181178A1

公开(公告)日：2012-07-19

申请号：US13316985

申请日：2011-12-12

申请人： Alberto LAMAGNA ,  Maximiliano Sebastián PÉREZ ,  Betiana Lerner ,  Claudio Berli ,  Andrés Felipe ORDONEZ ,  Alfredo BOSELLI ,  Francisco SACCO ,  Elda Maria SALMORAL ,  Andrés KREINER ,  Carlos Alberto RINALDI ,  Carlos LASORSA

发明人： Alberto LAMAGNA ,  Maximiliano Sebastián PÉREZ ,  Betiana Lerner ,  Claudio Berli ,  Andrés Felipe ORDONEZ ,  Alfredo BOSELLI ,  Francisco SACCO ,  Elda Maria SALMORAL ,  Andrés KREINER ,  Carlos Alberto RINALDI ,  Carlos LASORSA

IPC分类号： C25B7/00

CPC分类号： G01N27/4473

摘要： A fluidic device is disclosed for making electrophoresis of molecules. The device has channels of closed geometry and variable powers over time. Migration of molecules is contained within channel of closed geometry, whereby they can circulate again and again, thus separating the molecules at a wide migration distance. The device has an injection system which is a secondary channel which intersects the main channel. An arrangement of electrodes along this main channel connected to a variable voltage source with multiple outlets which regulates the value of the electric power in each electrode, and the frequency at which the same varies from one electrode to another. Thus it is achieved to generate a periodic arrangement of powers along the channel which set the flow of the sample optimizing the separation process. Electrodes can be added for the detection of molecules by measuring the changes in electric resistivity, current or voltage.

摘要翻译： 公开了用于进行分子电泳的流体装置。 该设备具有封闭几何通道和随时间变化的功率。 分子的迁移包含在封闭几何形状的通道内，由此它们可以一次又一次地循环，从而以宽的迁移距离分离分子。 该装置具有与主通道相交的次级通道的注射系统。 沿着该主通道的电极的布置连接到具有多个出口的可变电压源，所述多个出口调节每个电极中的电力值，以及相同的频率从一个电极到另一个电极的频率。 因此，实现沿着通道产生功率的周期布置，其设定样品的流动优化分离过程。 可以通过测量电阻率，电流或电压的变化来添加电极以检测分子。