公开(公告)号：US06509169B2

公开(公告)日：2003-01-21

申请号：US09903902

申请日：2001-07-12

Applicant: Norman M. Ratcliffe ,  Clive Teare ,  Christopher Dunn ,  David C. Cowell ,  Caroline Penault ,  Paul Chambers ,  Murdo M. Black

Inventor： Norman M. Ratcliffe ,  Clive Teare ,  Christopher Dunn ,  David C. Cowell ,  Caroline Penault ,  Paul Chambers ,  Murdo M. Black

IPC: C12Q104

CPC classification number: A61B5/4216 ,  A61B5/097 ,  G01N27/12 ,  G01N33/0054 ,  G01N33/497 ,  Y02A50/246

Abstract: A method for detecting Helicobacter pylori in a subject's gastroenteral tract involves measuring a change in resistance of an electronic or electrochemical sensor, notably a polypyrrole film, on exposure to gas from the subject's lungs and/or stomach. Depending on the magnitude of the change (if any) a positive or negative result is indicated visually by electronics means. Two sensors are used, one of which receives a sample of gas which has passed through an amonia-absorbing means to provide a corrected baseline value for the ammonia. The invention also provides apparatus suitable for carrying out the method.

Abstract translation: 用于检测受试者胃肠道中的幽门螺杆菌的方法包括在暴露于来自受试者的肺和/或胃的气体时测量电子或电化学传感器，特别是聚吡咯膜的电阻变化。 根据变化的大小（如果有的话），电子手段可以直观地指出正或负的结果。 使用两个传感器，其中一个接收已经通过氨基酸吸收装置的气体样品，以提供校正的氨的基准值。 本发明还提供适用于实施该方法的设备。