公开(公告)号：US20080017577A1

公开(公告)日：2008-01-24

申请号：US11459076

申请日：2006-07-21

Applicant: Jizu Yi ,  Fu Chung Lin ,  Dimitrios Manoussakis ,  Craig Gelfand

Inventor： Jizu Yi ,  Fu Chung Lin ,  Dimitrios Manoussakis ,  Craig Gelfand

IPC: B01D61/18

CPC classification number: B01L3/50825 ,  B01L3/502 ,  B01L3/5021 ,  B01L2300/047 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2400/049

Abstract: The fluid sample collection device is adapted to collect and separate a fluid sample into constituent parts such as separating plasma or serum from a blood sample. The device includes an evacuated outer container and an inner container. The outer container has a first open end and a second closed end. A pierceable closure closes the first open end thereby defining a first interior chamber. The inner container is contained within the outer container and separates the first interior chamber into an upper chamber portion and lower chamber portion in fluid communication. The inner container defines a second interior chamber separated from the lower chamber portion through a porous membrane. A port is provided for placing the second interior chamber in fluid communication with the first interior chamber. Another aspect of the device relates to a method of using the device to separate plasma or serum from a blood sample.

Abstract translation: 流体样品收集装置适于将流体样品收集并分离成组成部分，例如从血液样品分离血浆或血清。 该装置包括抽真空的外部容器和内部容器。 外容器具有第一开口端和第二闭合端。 可刺破的封闭件封闭第一开口端，由此限定第一内部腔室。 内部容器被容纳在外部容器内并且将第一内部腔室分离成上部腔室部分和下部腔室部分，以使其流体连通。 内部容器限定通过多孔膜与下部室分隔开的第二内部室。 提供端口用于将第二内部腔室与第一内部腔室流体连通。 该装置的另一方面涉及使用该装置将血浆或血清与血液样品分离的方法。

公开(公告)号：US20070264671A1

公开(公告)日：2007-11-15

申请号：US11724029

申请日：2007-03-13

Applicant: Patrick O'Mullan ,  Craig Gelfand

Inventor： Patrick O'Mullan ,  Craig Gelfand

IPC: C12Q1/37 ,  G01N33/573

CPC classification number: G01N33/573 ,  C12Q1/37 ,  G01N33/6893 ,  G01N2800/042

Abstract: A method is provided for the diagnosis or prognosis of a disease state, involving the measurement of a parameter of discriminated dipeptidyl dipeptidases from a patient sample, and the correlation of the parameter with a disease.

Abstract translation: 提供了用于疾病状态的诊断或预后的方法，涉及从患者样品测量鉴别的二肽基二肽酶的参数以及参数与疾病的相关性。

公开(公告)号：US20050176032A1

公开(公告)日：2005-08-11

申请号：US10983568

申请日：2004-11-08

Applicant: Kenneth Breslauer ,  Craig Gelfand ,  G. Plum

Inventor： Kenneth Breslauer ,  Craig Gelfand ,  G. Plum

IPC: C12Q1/68 ,  G01N31/16

CPC classification number: C12Q1/6818 ,  C12Q1/68 ,  C12Q1/6827 ,  G01N31/16 ,  C12Q2537/161 ,  C12Q2527/101 ,  C12Q2565/101

Abstract: Simple methods and kits for determining the thermodynamic stability of nucleic acid duplexes and single polynucleotide polymorphisms via competitive equilibria are provided.

Abstract translation: 提供了用于通过竞争平衡确定核酸双链体和单个多核苷酸多态性的热力学稳定性的简单方法和试剂盒。