公开(公告)号：US20150065454A1

公开(公告)日：2015-03-05

申请号：US14361400

申请日：2012-11-30

申请人： Cytosial Biomedic ,  Universite Jean Monnet ,  Institut National des Sciences Appliquees de Lyon ,  Universite Claude Bernard Lyon 1 ,  Centre National de la Recherche Scientifique (CNRS

发明人： Florence Dupasquier ,  Laurent David ,  Thierry Delair

IPC分类号： A61L27/20 ,  A61Q19/08 ,  A61K8/73 ,  A61L27/58 ,  A61L27/54

CPC分类号： A61L27/20 ,  A61K8/736 ,  A61K2800/91 ,  A61L24/08 ,  A61L27/54 ,  A61L27/58 ,  A61L31/04 ,  A61L31/042 ,  A61L2300/402 ,  A61L2300/416 ,  A61L2300/63 ,  A61L2400/06 ,  A61L2430/34 ,  A61Q19/08 ,  C08L5/04

摘要： The present invention relates to a homogeneous aqueous solution of injectable chitosan containing a chitosan having a degree of acetylation lower than 20%, said solution containing between 0.1 and 3.5% by weight of chitosan, said solution presenting a pH lower than 6.2, and said aqueous solution being capable of forming crystalline particles of chitosan after injection. The present invention also relates to compounds containing such a homogeneous aqueous solution of chitosan. The invention also relates to such compounds for their use as dermatological or cosmetic compounds, or for their use as a medical device, advantageously as a bioresorbable implant.

摘要翻译： 本发明涉及含有乙酰化度低于20％的壳聚糖的均匀的可注射壳聚糖水溶液，所述溶液含有0.1至3.5重量％的壳聚糖，所述溶液的pH低于6.2，所述水溶液 溶液能够在注射后形成壳聚糖的结晶颗粒。 本发明还涉及含有这种均匀的壳聚糖水溶液的化合物。 本发明还涉及用作皮肤病学或化妆品化合物或用作医疗器械的这些化合物，有利地作为生物可再吸收的植入物。