公开(公告)号：US20060264478A1

公开(公告)日：2006-11-23

申请号：US11359726

申请日：2006-02-22

Applicant: D. Surmeier ,  Michelle Day ,  Jun Ding ,  Savio Chan ,  Jamie Guzman ,  Jeff Mercer ,  Tatiana Tkatch ,  Zhongfeng Wang ,  Ema Ilijic

Inventor： D. Surmeier ,  Michelle Day ,  Jun Ding ,  Savio Chan ,  Jamie Guzman ,  Jeff Mercer ,  Tatiana Tkatch ,  Zhongfeng Wang ,  Ema Ilijic

IPC: A61K31/455 ,  C12Q1/68

CPC classification number: A61K31/4439 ,  A61K31/554 ,  A61K45/06 ,  G01N33/48 ,  G01N33/6872 ,  G01N2500/04

Abstract: The present invention relates to methods and compositions for modulating calcium channels. In particular, the present invention provides methods and compositions for modulating (e.g., disrupting) Cav1.3a calcium channels for research and therapeutic methods (e.g., treating dopaminergic diseases and conditions).

Abstract translation: 本发明涉及调节钙通道的方法和组合物。 特别地，本发明提供用于调节（例如，破坏）Cav1.3a钙通道用于研究和治疗方法（例如治疗多巴胺能疾病和病症）的方法和组合物。