公开(公告)号：US09670277B2

公开(公告)日：2017-06-06

申请号：US14001594

申请日：2012-02-24

申请人： Reza Dana ,  Daniel Saban

发明人： Reza Dana ,  Daniel Saban

IPC分类号： C07K16/28 ,  A61K9/00 ,  A61K38/19 ,  A61K39/00

CPC分类号： A61K38/195 ,  A61K9/0048 ,  A61K31/433 ,  A61K31/496 ,  A61K2039/505 ,  C07K16/28 ,  C07K16/2866 ,  C07K2317/76

摘要： This application discloses ophthalmic formulations and methods for treating inflammatory disease and conditions of the ocular surface with one or more C—C chemokine receptor type 7 (CCR7) antagonists. The compositions may be formulated for subconjunctival or topical administration to the eye and are effective in the treatment of inflammatory disease and conditions of the ocular surface.

公开(公告)号：US20140147449A1

公开(公告)日：2014-05-29

申请号：US14001594

申请日：2012-02-24

申请人： Reza Dana ,  Daniel Saban

发明人： Reza Dana ,  Daniel Saban

IPC分类号： C07K16/28 ,  A61K9/00

CPC分类号： A61K38/195 ,  A61K9/0048 ,  A61K31/433 ,  A61K31/496 ,  A61K2039/505 ,  C07K16/28 ,  C07K16/2866 ,  C07K2317/76

摘要： This application discloses ophthalmic formulations and methods for treating inflammatory disease and conditions of the ocular surface with one or more C-C chemokine receptor type 7 (CCR7) antagonists. The compositions may be formulated for subconjunctival or topical administration to the eye and are effective in the treatment of inflammatory disease and conditions of the ocular surface.

摘要翻译： 本申请公开了一种用一种或多种C-C趋化因子受体7型（CCR7）拮抗剂治疗炎症性疾病和眼表的病症的眼用制剂和方法。 组合物可以配制成用于结膜下或局部施用于眼睛，并且有效治疗炎症性疾病和眼表面状况。

公开(公告)号：US20070018516A1

公开(公告)日：2007-01-25

申请号：US11188915

申请日：2005-07-25

申请人： Debabrata Pal ,  Laurence Vanek ,  Daniel Saban

发明人： Debabrata Pal ,  Laurence Vanek ,  Daniel Saban

IPC分类号： H02K9/00 ,  H02K1/32

CPC分类号： F02C7/12 ,  F04D25/06 ,  F04D25/082 ,  F04D29/5806 ,  F04D29/584 ,  H02K7/14 ,  H02K9/10 ,  H02K9/22

摘要： A motor driven assembly includes a motor having a motor shaft mounted for rotation about a rotational axis and a rotor radially located about the shaft. The motor drives a compressor that receives air from the motor, compresses the air, and circulates the compressed air to a space. The motor includes a first cooling flow passage and a second cooling flow passage that each receive air to provide internal cooling of the motor. A portion of the air compressed in the compressor is diverted from the compressor to a heat exchanger. The heat exchanger cools the compressed air from before the air circulates into the first cooling flow passage to cool the motor. The second cooling flow passage receives air from the environment surrounding the motor driven assembly to further cool the motor.

摘要翻译： 电动机驱动组件包括具有安装用于围绕旋转轴线旋转的电动机轴和绕轴径向定位的转子的电动机。 电动机驱动从电动机接收空气的压缩机，压缩空气，并将压缩空气循环到空间。 电动机包括第一冷却流路和第二冷却流路，每个第一冷却流路和第二冷却流路都接收空气以提供电动机的内部冷却。 在压缩机中压缩的空气的一部分从压缩机转移到热交换器。 热交换器将空气从空气循环进入第一冷却流路之前冷却压缩空气以冷却马达。 第二冷却流路从围绕马达驱动组件的环境接收空气，以进一步冷却马达。