公开(公告)号：US08591948B2

公开(公告)日：2013-11-26

申请号：US11445849

申请日：2006-06-01

申请人： Lieven Elvire Colette Baert ,  Geert Verreck ,  Dany Thoné

发明人： Lieven Elvire Colette Baert ,  Geert Verreck ,  Dany Thoné

IPC分类号： A61K9/36 ,  A61K9/20 ,  A61K9/28 ,  A61K9/30 ,  A61K31/497

CPC分类号： A61K9/146 ,  A61K9/1652 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2077 ,  A61K9/2866 ,  A61K31/496

摘要： The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.

公开(公告)号：US07081255B2

公开(公告)日：2006-07-25

申请号：US10218851

申请日：2002-08-14

申请人： Lieven Elvire Colette Baert ,  Geert Verreck ,  Dany Thoné

发明人： Lieven Elvire Colette Baert ,  Geert Verreck ,  Dany Thoné

IPC分类号： A61K9/36 ,  A61K9/20 ,  A61K9/28 ,  A61K9/30 ,  A61K31/497

CPC分类号： A61K9/146 ,  A61K9/1652 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2077 ,  A61K9/2866 ,  A61K31/496

摘要： The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.

公开(公告)号：US06509038B2

公开(公告)日：2003-01-21

申请号：US09194480

申请日：1998-11-19

申请人： Lieven Elvire Colette Baert ,  Geert Verreck ,  Dany Thoné

发明人： Lieven Elvire Colette Baert ,  Geert Verreck ,  Dany Thoné

IPC分类号： A61K936

CPC分类号： A61K9/146 ,  A61K9/1652 ,  A61K9/2027 ,  A61K9/2054 ,  A61K9/2077 ,  A61K9/2866 ,  A61K31/496

摘要： The present invention is concerned with novel pharmaceutical compositions of itraconazole which can be administered to a mammal suffering from a fungal infection, whereby a single such dosage form can be administered once daily, and in addition at any time of the day independently of the food taken in by said mammal. These novel compositions comprise particles obtainable by melt-extruding a mixture comprising itraconazole and an appropriate water-soluble polymer and subsequently milling said melt-extruded mixture.