公开(公告)号：US06320025B1

公开(公告)日：2001-11-20

申请号：US09354760

申请日：1999-07-29

Applicant: Dario Slavazza ,  Heng Wei Chang

Inventor： Dario Slavazza ,  Heng Wei Chang

IPC: A61K3800

CPC classification number: C07K1/045 ,  B01D2201/0438 ,  B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00351 ,  B01J2219/00353 ,  B01J2219/00389 ,  B01J2219/00423 ,  B01J2219/00481 ,  B01J2219/005 ,  B01J2219/00596 ,  B01J2219/00725 ,  C40B40/10 ,  C40B60/14

Abstract: Reaction vessels suitable for solid phase polymer synthesis generally comprise: a housing defining a chamber for containing a resin, said housing having an operable inlet port and an operable outlet port in fluid communication with said chamber; and an elongate resin filter having an interior bore, and adapted to enable filtered fluid flow from an exterior inlet surface thereof into the filter interior bore, said filter being disposed in said chamber and having an outlet connection fluidly coupling said filter interior bore to the housing outlet port such that fluid flowing through the housing inlet port into the chamber passes through the filter inlet surface, into the filter interior bore and out the housing outlet port.

Abstract translation: 适用于固相聚合物合成的反应容器通常包括：限定用于容纳树脂的室的壳体，所述壳体具有可操作的入口端口和与所述室流体连通的可操作的出口端口; 以及细长的树脂过滤器，其具有内孔，并且适于使过滤的流体从其外部入口表面流入过滤器内部孔，所述过滤器设置在所述室中并且具有将所述过滤器内部孔流体连接到壳体 出口端口，使得流过壳体入口的流体进入室通过过滤器入口表面，进入过滤器内部孔并从壳体出口端口出来。