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公开(公告)号：US08269025B2
公开(公告)日：2012-09-18
申请号：US12481287
申请日：2009-06-09
申请人： Nadya Belcheva , Trang Huynh , Darlene Nebinger , Ronald Rutka
发明人： Nadya Belcheva , Trang Huynh , Darlene Nebinger , Ronald Rutka
IPC分类号： C07D319/12
CPC分类号： C07D319/12
摘要： The present disclosure provides methods for purifying p-dioxanone. In embodiments, crude p-dioxanone may be contacted with at least one isocyanate-functionalized scavenger. The at least one isocyanate-functionalized scavenger may react with hydroxyl compounds present with the crude p-dioxanone to form reaction products, in embodiments polyurethanes and/or polyureas, which may then be removed. The p-dioxanone thus obtained is of greater purity than the starting crude p-dioxanone.
摘要翻译： 本公开提供了对二恶烷酮的纯化方法。 在实施方案中，粗对二氧杂环己酮可以与至少一种异氰酸酯官能化的清除剂接触。 至少一种异氰酸酯官能化的清除剂可与存在于粗对二恶烷酮中的羟基化合物反应以形成反应产物，在实施方案中可以除去聚氨酯和/或聚脲。 由此获得的对二恶烷酮的纯度比起始粗对二恶烷酮的纯度高。
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公开(公告)号：US20100004471A1
公开(公告)日：2010-01-07
申请号：US12481287
申请日：2009-06-09
申请人： Nadya Belcheva , Trang Huynh , Darlene Nebinger , Ronald Rutka
发明人： Nadya Belcheva , Trang Huynh , Darlene Nebinger , Ronald Rutka
IPC分类号： C07D319/12
CPC分类号： C07D319/12
摘要： The present disclosure provides methods for purifying p-dioxanone. In embodiments, crude p-dioxanone may be contacted with at least one isocyanate-functionalized scavenger. The at least one isocyanate-functionalized scavenger may react with hydroxyl compounds present with the crude p-dioxanone to form reaction products, in embodiments polyurethanes and/or polyureas, which may then be removed. The p-dioxanone thus obtained is of greater purity than the starting crude p-dioxanone.
摘要翻译： 本公开提供了对二恶烷酮的纯化方法。 在实施方案中，粗对二氧杂环己酮可以与至少一种异氰酸酯官能化的清除剂接触。 至少一种异氰酸酯官能化的清除剂可与存在于粗对二恶烷酮中的羟基化合物反应以形成反应产物，在实施方案中可以除去聚氨酯和/或聚脲。 由此获得的对二恶烷酮的纯度比起始粗对二恶烷酮的纯度高。
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公开(公告)号：US08968362B2
公开(公告)日：2015-03-03
申请号：US13045618
申请日：2011-03-11
CPC分类号： A61B17/06166 , A61B17/0401 , A61B2017/00526 , A61B2017/06176 , A61L17/12 , A61L17/145
摘要： A suture including a reinforced loop is described herein. The suture includes an elongate body including a proximal section and a distal section, wherein the distal section includes first and second overlapping sections and a loop. A polymeric coating is positioned on at least a portion of the distal section to reinforce the loop.
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公开(公告)号：US20110251639A1
公开(公告)日：2011-10-13
申请号：US13045618
申请日：2011-03-11
IPC分类号： A61L17/00
CPC分类号： A61B17/06166 , A61B17/0401 , A61B2017/00526 , A61B2017/06176 , A61L17/12 , A61L17/145
摘要： A suture including a reinforced loop is described herein. The suture includes an elongate body including a proximal section and a distal section, wherein the distal section includes first and second overlapping sections and a loop. A polymeric coating is positioned on at least a portion of the distal section to reinforce the loop.
摘要翻译： 本文描述了包括加强环的缝合线。 缝合线包括细长体，其包括近端部分和远端部分，其中远侧部分包括第一和第二重叠部分和环。 聚合物涂层定位在远端部分的至少一部分上以加强环路。
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