公开(公告)号：US20070287178A1

公开(公告)日：2007-12-13

申请号：US11449344

申请日：2006-06-08

Applicant: David James Beebe ,  Hongmei Yu ,  Caroline Alexander

Inventor： David James Beebe ,  Hongmei Yu ,  Caroline Alexander

IPC: C12N5/02

CPC classification number: C12N5/0062

Abstract: Co-cultures of heterogeneous cell populations in a diffusion-constrained microenvironment and methods for co-culturing are disclosed.

Abstract translation: 公开了扩散受限微环境中异源细胞群体的共培养和共培养方法。

公开(公告)号：US20150087006A1

公开(公告)日：2015-03-26

申请号：US14491701

申请日：2014-09-19

Applicant: Chorom Pak ,  Edmond Wai Keung Young ,  Natalie Callander ,  David James Beebe ,  Shigeki Miyamoto

Inventor： Chorom Pak ,  Edmond Wai Keung Young ,  Natalie Callander ,  David James Beebe ,  Shigeki Miyamoto

IPC: G01N33/50

CPC classification number: G01N33/5008 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0472 ,  C12M23/16 ,  G01N33/5044 ,  G01N33/54366 ,  G01N33/57426 ,  G01N2500/04

Abstract: The invention relates to systems and methods for studying patient cancer samples in cis-co-culture. For example, the invention provide systems and methods for testing therapeutic agents in vitro in an environment that simulates an in vivo environment to identify agents that are therapeutically effective for the patient.

Abstract translation: 本发明涉及用于研究顺式共培养中的患者癌症样品的系统和方法。 例如，本发明提供了在模拟体内环境以鉴定对患者有治疗效力的药剂的环境中体外测试治疗剂的系统和方法。

公开(公告)号：US08124410B2

公开(公告)日：2012-02-28

申请号：US11449344

申请日：2006-06-08

Applicant: David James Beebe ,  Hongmei Yu ,  Caroline Alexander

Inventor： David James Beebe ,  Hongmei Yu ,  Caroline Alexander

IPC: C12N5/02

CPC classification number: C12N5/0062

Abstract: Co-cultures of heterogeneous cell populations in a diffusion-constrained microenvironment and methods for co-culturing are disclosed.

Abstract translation: 公开了扩散受限微环境中异源细胞群体的共培养和共培养方法。