Method And System For Using Cherenkov Radiation To Monitor Beam Profiles And Radiation Therapy
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    发明申请
    Method And System For Using Cherenkov Radiation To Monitor Beam Profiles And Radiation Therapy 审中-公开
    使用切伦科夫辐射监测光束形貌和放射治疗的方法和系统

    公开(公告)号:US20140114150A1

    公开(公告)日:2014-04-24

    申请号:US14118825

    申请日:2012-05-18

    摘要: A system for providing monitored radiation therapy has a high energy radiation source, apparatus for excluding uncontrolled ambient light, and apparatus for collecting light emitted from a subject. The system has apparatus for spectrally analyzing the collected light, and a processor for determining oxygenation or other metabolic function of tissue within the subject from spectral analysis of the collected light. The system monitors radiation therapy by providing a beam of high energy radiation; collecting Cherenkov and/or photoluminescent light from the subject, the light generated along the beam; spectrally analyzing the light; and determining oxygenation or metabolic function of tissue from the spectral analysis. Beam profile of the system is calibrated by imaging from multiple angles Cherenkov and/or photoluminescent light emitted by a phantom placed in the beam in lieu of a subject, captured images are analyzed to determine beam profile.

    摘要翻译: 用于提供监测的放射治疗的系统具有高能量辐射源,用于排除不受控制的环境光的装置,以及用于收集从受试者发射的光的装置。 该系统具有用于对收集的光进行光谱分析的装置,以及用于通过所收集的光的光谱分析来确定受试者内组织的氧合或其它代谢功能的处理器。 该系统通过提供高能辐射束来监测放射治疗; 从受试者收集切伦科夫和/或光致发光,沿着光束产生的光; 光谱分析光; 并从光谱分析中确定组织的氧合作用或代谢功能。 系统的光束轮廓通过从多个角度成像Cherenkov和/或通过放置在光束中的幻影发射的光致发光来代替被摄体来校准,捕获的图像被分析以确定光束轮廓。