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1.发明授权Non-invasive determination of analyte concentration using non-continuous radiation 失效使用非连续辐射非侵入性测定分析物浓度
公开(公告)号：US5360004A
公开(公告)日：1994-11-01
申请号：US59164
申请日：1993-05-07
申请人： David L. Purdy , Richard L. Wiggins , Paul Castro
发明人： David L. Purdy , Richard L. Wiggins , Paul Castro
CPC分类号： G01N21/359 , A61B5/14532 , A61B5/1455
摘要： A method and apparatus for non-invasive determination of the concentration of at least one analyte in a mammal. A portion of the body of the mammal is irradiated with incident radiation, where the incident radiation includes two or more distinct bands of continuous-wavelength incident radiation. The resulting radiation emitted from the portion of the body is sensed and a value for the concentration of the analyte is derived therefrom.
摘要翻译： 用于非侵入式确定哺乳动物中至少一种分析物的浓度的方法和装置。 用入射辐射照射哺乳动物身体的一部分，其中入射辐射包括两个或更多个不同的连续波长入射辐射带。 感测从身体部分发射的所产生的辐射，并从中得到分析物浓度的值。
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公开(公告)号：US4892518A
公开(公告)日：1990-01-09
申请号：US128890
申请日：1987-12-04
CPC分类号： A61M39/0208 , A61M1/16 , A61M2039/0211 , Y10T137/7891
摘要： Hemodialysis port assembly including a port and a catheter assembly. The port includes an inlet septum subtended by an inlet plenum and an outlet septum subtended by an outlet plenum. The catheter assembly includes an inlet channel connected to the inlet plenum and an outlet channel connected to the outlet plenum. The port and catheter assembly are completely implanted in the chest of a patient with the port subcutaneous and the end of the catheter assembly remote from the port injected into the subclavian vein. The blood flow in this vein is in the direction away from the end of the catheter assembly. Near this remote end the catheter assembly or the inlet channel terminates in an inlet valve and the outlet channel terminates in an outlet valve. Each of these valves is essentially a flapper on which the blood is incident in a generally perpendicular direction so that its flow is substantially unimpeded. The outlet valve is spaced a small but effective distance from the inlet valve in the downstream direction of the flow to toxified blood through the outlet channel. In practice of this invention, the detoxified blood from an artificial kidney is supplied to the vein through a hypodermic needle which penetrates the inlet septum, the inlet plenum, the inlet channel and the inlet valve and toxified blood is supplied from the vein to the artificial kidney through the outlet valve, the outlet channel, the outlet plenum and an outlet needle which penetrates the outlet septum. The spacing of the outlet valve from the inlet valve suppresses short-circuit flow of detoxified blood from the inlet branch to the outlet branch.
摘要翻译： 血液透析端口组件包括端口和导管组件。 该端口包括入口隔室对面的入口隔膜和由出口增压室对着的出口隔膜。 导管组件包括连接到入口气室的入口通道和连接到出口增压室的出口通道。 端口和导管组件完全植入患者的胸部，皮下端口和导管组件的端部远离注入锁骨下静脉的口。 该静脉中的血液流动方向远离导管组件的端部。 在该远端附近，导管组件或入口通道终止于入口阀，并且出口通道终止于出口阀。 这些阀中的每一个基本上是挡板，血液沿着大致垂直的方向入射，使得其流动基本上不受阻碍。 出口阀在通向出口通道的有毒血液流向下游方向与入口阀隔开一段小而有效的距离。 在本发明的实践中，来自人造肾的解毒血液通过渗透入口隔膜，入口通气室，入口通道和入口阀的皮下注射针供给到静脉，并且有毒血液从静脉供应到人造 肾通过出口阀，出口通道，出口增压室和穿过出口隔膜的出口针头。 出口阀与入口阀的间距抑制了从入口分支到出口分支的解毒血液的短路流动。
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公开(公告)号：US4006039A
公开(公告)日：1977-02-01
申请号：US631588
申请日：1975-11-13
申请人： David L. Purdy
发明人： David L. Purdy
摘要： In a thermoelectric generator, a component comprises a ceramic insulator, having over limited areas thereof, each area corresponding to a terminal end of thermoelectric wires, a coating of a first metal which adheres to the insulator, and an electrical thermoelectric junction including a second metal which wets said first metal and adheres to said terminal ends but does not wet said insulator, and a cloth composed of electrically insulating threads interlaced with thermoelectric wires.
摘要翻译： 在热电发电机中，部件包括陶瓷绝缘体，其具有超过限定的区域，每个区域对应于热电电线的末端，附着于绝缘体的第一金属的涂层和包括第二金属 其浸渍所述第一金属并粘附到所述末端，但不会湿润所述绝缘体，以及由与电热丝交织的电绝缘线构成的布。
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公开(公告)号：US3987799A
公开(公告)日：1976-10-26
申请号：US550071
申请日：1975-02-14
摘要： A heart pacer to be implanted between the pectoralis major muscle and the skin a short distance below the clavicle having an outer container in the shape of an ovaloid. Such a heart pacer adapts itself positionally, cosmetically and with a minimum of discomfort to implantation.
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公开(公告)号：US5562729A
公开(公告)日：1996-10-08
申请号：US332720
申请日：1994-11-01
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , Y10S623/90
摘要： A multi-leaflet (usually trileaflet) heart valve composed of biocompatible polymer which, in all of its embodiments, simultaneously imitates the structure and dynamics of biological heart valves and avoids promotion of calcification. The valve includes a plurality of flexible leaflets dip cast on a mandrel, which leaflets are then bonded with a bonding agent to the interior surfaces of a plurality of struts on a metal-reinforced prosthetic stent. The leaflets open and close in response to the pumping action of the heart and, due to the design of the leaflets, fatigue resistance of the heart valve is high. The leaflets and the polymer components of the prosthetic stent are manufactured of biocompatible polymers exhibiting intrinsic calcification-resistant properties.
摘要翻译： 一种由生物相容性聚合物组成的多叶（通常是三叶草）心脏瓣膜，其在其所有实施方案中同时模仿生物心脏瓣膜的结构和动力学并避免促进钙化。 阀包括浸在心轴上的多个柔性传单，然后将这些小叶与粘合剂结合到金属增强的假体支架上的多个支柱的内表面上。 响应于心脏的泵送动作，传单打开和关闭，并且由于小叶的设计，心脏瓣膜的抗疲劳性高。 假体支架的传单和聚合物组分由表现出固有的抗钙化特性的生物相容性聚合物制成。
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公开(公告)号：US4006038A
公开(公告)日：1977-02-01
申请号：US631587
申请日：1975-11-13
申请人： David L. Purdy
发明人： David L. Purdy
摘要： Threads are interlaced with thermoelectric wires to provide a woven cloth in tape form, there being an intermediate layer of heat radiation reflecting material (e.g., aluminum foil) insulated electrically from said wires, which are of opposite thermoelectric polarity and connected as a plurality of thermocouples.
摘要翻译： 螺纹与热电电线交织以提供带状的编织布，其中具有与所述导线绝缘的热辐射反射材料（例如，铝箔）的中间层，其与热电极性相反并且作为多个热电偶 。
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7.发明授权Method for non-invasive measurement of concentration of analytes in blood using continuous spectrum radiation 失效使用连续光谱辐射非侵入式测量血液中分析物浓度的方法
公开(公告)号：US5460177A
公开(公告)日：1995-10-24
申请号：US59162
申请日：1993-05-07
申请人： David L. Purdy , Perry Palumbo , Mark DiFrancesco
发明人： David L. Purdy , Perry Palumbo , Mark DiFrancesco
CPC分类号： A61B5/1455 , A61B5/14532 , G01N21/31 , G01J3/2803 , G01N21/35 , G01N21/359
摘要： Method for non-invasive detection of the concentration of a constituent in blood of a living animal includes the steps of irradiating a body part of the animal with intensity-modulated radiation over a continuous spectrum; determining the intensity of radiation emitted from the body part at wavelength ranges within the continuous spectrum; and using the determined intensity to calculate the concentration of the constituent. A radiation source including a radiating bulb and a chopper for periodically interrupting radiation emitted from the bulb may be provided.
摘要翻译： 用于非侵入性检测活体血液中成分浓度的方法包括以下步骤：用强度调制的辐射在连续光谱上照射动物的身体部分; 确定在连续光谱内的波长范围内从身体部分发射的辐射的强度; 并使用确定的强度来计算组分的浓度。 可以提供包括用于周期性地中断从灯泡发射的辐射的辐射灯泡和斩波器的辐射源。
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公开(公告)号：US5070874A
公开(公告)日：1991-12-10
申请号：US482792
申请日：1990-01-30
CPC分类号： A61B5/1455 , A61B5/14532 , G01J3/433
摘要： Radiation in the near infrared over a limited range of wavelengths about 1660 nanometers is projected on a portion of the body, for example, the ear, of the patient. The resulting radiation emitted by the portion, either scattered from the portion or transmitted after absorption and scattered by the portion, is processed to derive an expression of the resulting radiation as a function of the wavelength. The second derivative of this function over a very narrow range of this function between 1640 and 1670 nanometers is expanded and the glucose concentration is determined from the magnitude, or intensity, of the scattered or transmitted radiation at the maximum or minimum point of this derivative apparatus for non-invasive determination of glucose concentration in the patient. Radiation in the near infrared is transmitted through a first fiber-optic radiation conductor to the outer surface of a portion of the patient's body, penetrating into the portion. A second fiber-optic conductor transmits the resulting radiation emitted from the portion to data processing means which produces the desired second derivative as a function of the wavelength of the incident radiation. The processor includes a spectrum analyzer which produces a spectrum of the resulting radiation.
摘要翻译： 在约1660纳米的有限的波长范围内的近红外线的辐射被投射在患者身体的一部分，例如耳朵上。 由该部分发射的或者从该部分散射或在吸收之后透射并由该部分散射的所产生的辐射是根据波长导出所得辐射的表达的过程。 在1640和1670纳米之间的这个功能的非常狭窄的范围内，该函数的二阶导数被扩展，并且葡萄糖浓度是根据该导数的最大或最小点处的散射或透射辐射的幅度或强度来确定的。 用于非侵入性测定患者葡萄糖浓度的装置。 近红外线的辐射通过第一光纤辐射导体传播到患者身体的一部分的外表面，穿透入该部分。 第二光纤导体将从该部分发射的所得到的辐射传输到数据处理装置，该数据处理装置产生作为入射辐射的波长的函数的所需二阶导数。 该处理器包括产生所得辐射光谱的频谱分析仪。
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公开(公告)号：US4907593A
公开(公告)日：1990-03-13
申请号：US52262
申请日：1987-05-21
IPC分类号： A61N1/365
CPC分类号： A61N1/36514
摘要： A rate-changing implantable heart-stimulating device is disclosed, one that avoids use of moving parts and making unwanted rate changes. The device senses and responds to skeletal myopotential signals derived from the body of the wearer, preferably considering both amplitude and frequency of myopotential voltage signals which exceed a predetermined threshold value. The device preferably has two-way radio communication with an external programmer means.
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公开(公告)号：USRE30028E
公开(公告)日：1979-06-12
申请号：US758928
申请日：1977-01-13
摘要： A heart pacer to be implanted between the pectoralis major muscle and the skin a short distance below the clavicle having an outer container in the shape of an ovaloid.[...]. .Iadd.being, except where the heart lead is connected, curved in all dimensions and free of corners and shape ends. .Iaddend.Such a heart pacer adapts itself positionally, cosmetically and with a minimum of discomfort to implantation.
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