公开(公告)号：US09017396B2

公开(公告)日：2015-04-28

申请号：US10563387

申请日：2004-07-09

申请人： David Peter Shaw

发明人： David Peter Shaw

IPC分类号： A61F2/06 ,  A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2403 ,  A61F2/2475

摘要： A prosthetic valve in the form of a flap valve which includes one or more flaps arranged to allow movement of liquid through the valve only in one direction, in which the or each flap is made of a flexible open work structure of a medically acceptable metal such as titanium or a titanium alloy.

摘要翻译： 瓣瓣形式的假体瓣膜，其包括一个或多个翼片，其被设置成允许液体仅在一个方向上移动通过所述瓣膜，其中所述翼片或每个翼片由医学上可接受的金属的柔性开放的工作结构制成， 作为钛或钛合金。

公开(公告)号：US08206684B2

公开(公告)日：2012-06-26

申请号：US11067025

申请日：2005-02-25

申请人： John McCutcheon ,  Antony J. Fields ,  David Peter Shaw

发明人： John McCutcheon ,  Antony J. Fields ,  David Peter Shaw

IPC分类号： A61N33/44 ,  A61M11/00

CPC分类号： A61F5/00 ,  A61M11/00 ,  A61M16/0406 ,  A61M16/208 ,  A61M2210/1039

摘要： Disclosed is a method of regulating fluid flow for a targeted lung region. The method comprises injecting a therapeutic agent into the targeted lung region. The therapeutic agent induces a reaction in lung tissue of the targeted lung region or in a collateral pathway to the lung region to reduce collateral fluid flow into the targeted lung region. In one aspect, the method additionally comprises deploying a bronchial isolation device in the direct pathway to regulate fluid flow to the targeted lung region through the direct pathway. The therapeutic agent can comprise, for example, a sclerosing agent that induces a reaction that causes sclerosis in the lung tissue.

摘要翻译： 公开了一种调节目标肺部区域的流体流动的方法。 该方法包括将治疗剂注入靶向的肺部区域。 治疗剂诱导靶向肺部区域的肺组织或到肺部区域的旁路途径中的反应，以减少侧流体流入靶向肺区域。 在一个方面，该方法还包括在直接通路中部署支气管隔离装置，以通过直接通路调节流向目标肺区域的流体。 治疗剂可以包含例如诱导引起肺组织中的硬化的反应的硬化剂。

公开(公告)号：US20090255537A1

公开(公告)日：2009-10-15

申请号：US12490625

申请日：2009-06-24

申请人： David Peter Shaw ,  John McCutcheon ,  Antony J. Fields

发明人： David Peter Shaw ,  John McCutcheon ,  Antony J. Fields

IPC分类号： A62B9/02 ,  A61M31/00

CPC分类号： A61F2/04 ,  A61B17/12036 ,  A61B17/12104 ,  A61B17/12159 ,  A61B17/12172 ,  A61F2/24 ,  A61F2/82 ,  A61F2002/043

摘要： Disclosed are various disease indications and treatment methods that benefit from selective lung region isolation. A lung region is bronchially isolated by regulating the flow of fluid to and from the lung region, such as by implanting one or more bronchial isolation devices into one or more bronchial passageways that feed air to the lung region. The bronchial isolation devices can comprise, for example, one-way valves, two-way valves, occluders or blockers, ligating clips, glues, sealants, and sclerosing agents.

摘要翻译： 公开了从选择性肺区域分离中受益的各种疾病适应症和治疗方法。 通过调节流入和流出肺部区域的流体的流动，例如通过将一个或多个支气管隔离装置植入一个或多个向肺部区域进食空气的支气管通道，肺部区域被支气管分离。 支气管隔离装置可以包括例如单向阀，双向阀，闭塞器或阻塞器，结扎夹，胶水，密封剂和硬化剂。