-
公开(公告)号：US5756457A
公开(公告)日：1998-05-26
申请号：US435120
申请日：1995-05-05
CPC分类号： A61K38/1875 , A61L31/047 , A61L2430/32
摘要： Methods and devices are disclosed for inducing growth of neural cells, and repairing neural defects in a mammal. The method comprises administering to said mammal at the site of neural defect, damage or depletion, an effective amount of a bone morphogenetic protein, either in admixture with a pharmaceutically acceptable vehicle, or adsorbed to a suitable matrix. The device comprises bone morphogenetic protein, optionally in combination with other factors, adsorbed on a suitable matrix and contained within an artificial nerve replacement vessel.
摘要翻译： 公开了用于诱导神经细胞生长和修复哺乳动物神经缺陷的方法和装置。 该方法包括向所述哺乳动物施用神经缺陷，损伤或消耗的部位，有效量的骨形态发生蛋白，或者与药学上可接受的载体混合或吸附到合适的基质上。 该装置包括骨形态发生蛋白，任选地与其它因素组合，吸附在合适的基质上并且包含在人造神经置换容器内。
-
公开(公告)号：US10188812B2
公开(公告)日：2019-01-29
申请号：US14816779
申请日：2015-08-03
申请人： Dean M. Toriumi
发明人： Dean M. Toriumi
摘要： A nose clip includes an outer support member adapted to contact an outside surface of a nose; a bridge connected at a first end to the outer support member; and an inner support member connected to a second end of the bridge and adapted to be inserted into the nostril and to contact an inner surface of the nostril. When inserted, tension generated between the outer support member and the inner support member causes lateral movement of a surface within the nostril and opens a nasal airway. Additionally, the inner support can be curved to create an outward movement of the lateral wall of the nose. This in turn enables improved breathing. The nose clip may be made of a malleable material. The inner support member may include extensions that are malleable. The inner support members may be bent so that they create a convex contour of an interior surface of the nasal cavity. A different embodiment of the nose clip can be used to deliver drugs via a fluid filled cavity and porous surface that allows evaporation of the fluid and drug into the nasal cavity as air is drawn over the inner support member.
-
公开(公告)号：US09095674B2
公开(公告)日：2015-08-04
申请号：US12538388
申请日：2009-08-10
申请人： Dean M. Toriumi
发明人： Dean M. Toriumi
CPC分类号： A61M15/08 , A61F5/08 , A61M15/085
摘要： A nose clip includes an outer support member adapted to contact an outside surface of a nose. A bridge connected at a first end to the outer support member; and an inner support member connected to a second end of the bridge and adapted to be inserted into the nostril and to contact an inner surface of the nostril. When inserted, tension generated between the outer support member and the inner support member causes lateral movement of a surface within the nostril and opens a nasal airway. Additionally, the inner support can be curved to create an outward movement of the lateral wall of the nose. This in turn enables improved breathing.
摘要翻译： 鼻夹包括适于接触鼻子的外表面的外支撑构件。 一个桥，在第一端连接到外支撑件; 以及连接到所述桥的第二端并适于插入所述鼻孔并接触所述鼻孔的内表面的内部支撑构件。 当插入时，在外支撑构件和内支撑构件之间产生的张力导致鼻孔内的表面的横向运动并打开鼻气道。 另外，内支撑件可以弯曲以产生鼻部侧壁的向外运动。 这反过来又能改善呼吸。
-
公开(公告)号：US20150335462A1
公开(公告)日：2015-11-26
申请号：US14816779
申请日：2015-08-03
申请人： Dean M. Toriumi
发明人： Dean M. Toriumi
CPC分类号： A61M15/08 , A61F5/08 , A61M15/085
摘要： A nose clip includes an outer support member adapted to contact an outside surface of a nose; a bridge connected at a first end to the outer support member; and an inner support member connected to a second end of the bridge and adapted to be inserted into the nostril and to contact an inner surface of the nostril. When inserted, tension generated between the outer support member and the inner support member causes lateral movement of a surface within the nostril and opens a nasal airway. Additionally, the inner support can be curved to create an outward movement of the lateral wall of the nose. This in turn enables improved breathing. The nose clip may be made of a malleable material. The inner support member may include extensions that are malleable. The inner support members may be bent so that they create a convex contour of an interior surface of the nasal cavity. A different embodiment of the nose clip can be used to deliver drugs via a fluid filled cavity and porous surface that allows evaporation of the fluid and drug into the nasal cavity as air is drawn over the inner support member.
摘要翻译： 鼻夹包括适于接触鼻子的外表面的外支撑构件; 在第一端连接到外部支撑构件的桥; 以及连接到所述桥的第二端并适于插入所述鼻孔并接触所述鼻孔的内表面的内部支撑构件。 当插入时，在外支撑构件和内支撑构件之间产生的张力导致鼻孔内的表面的横向运动并打开鼻气道。 另外，内支撑件可以弯曲以产生鼻部侧壁的向外运动。 这反过来又能改善呼吸。 鼻夹可以由可延展材料制成。 内部支撑构件可以包括可延展的延伸部。 内部支撑构件可以被弯曲，使得它们产生鼻腔内表面的凸形轮廓。 鼻夹的不同实施例可以用于经由流体填充的空腔和多孔表面递送药物，当空气在内部支撑构件上被抽吸时，允许流体和药物蒸发到鼻腔中。
-
公开(公告)号：US20110034950A1
公开(公告)日：2011-02-10
申请号：US12538388
申请日：2009-08-10
申请人： Dean M. Toriumi
发明人： Dean M. Toriumi
CPC分类号： A61M15/08 , A61F5/08 , A61M15/085
摘要： A nose clip includes an outer support member adapted to contact an outside surface of a nose; a bridge connected at a first end to the outer support member; and an inner support member connected to a second end of the bridge and adapted to be inserted into the nostril and to contact an inner surface of the nostril. When inserted, tension generated between the outer support member and the inner support member causes lateral movement of a surface within the nostril and opens a nasal airway. Additionally, the inner support can be curved to create an outward movement of the lateral wall of the nose. This in turn enables improved breathing. The nose clip may be made of a malleable material. The inner support member may include extensions that are malleable. The inner support members may be bent so that they create a convex contour of an interior surface of the nasal cavity. A different embodiment of the nose clip can be used to deliver drugs via a fluid filled cavity and porous surface that allows evaporation of the fluid and drug into the nasal cavity as air is drawn over the inner support member.
摘要翻译： 鼻夹包括适于接触鼻子的外表面的外支撑构件; 在第一端连接到外部支撑构件的桥; 以及连接到所述桥的第二端并适于插入所述鼻孔并接触所述鼻孔的内表面的内部支撑构件。 当插入时，在外支撑构件和内支撑构件之间产生的张力导致鼻孔内的表面的横向运动并打开鼻气道。 另外，内支撑件可以弯曲以产生鼻部侧壁的向外运动。 这反过来又能改善呼吸。 鼻夹可以由可延展材料制成。 内部支撑构件可以包括可延展的延伸部。 内部支撑构件可以被弯曲，使得它们产生鼻腔内表面的凸形轮廓。 鼻夹的不同实施例可以用于经由流体填充的空腔和多孔表面递送药物，当空气在内部支撑构件上被抽吸时，允许流体和药物蒸发到鼻腔中。
-
-
-
-
搜索结果
5 条记录 (耗时 0.011 秒)
