公开(公告)号：US08979770B2

公开(公告)日：2015-03-17

申请号：US12280504

申请日：2007-02-15

申请人： Thomas L. Fare ,  Deborah A. Kessler ,  Kristopher A. Kilian

发明人： Thomas L. Fare ,  Deborah A. Kessler ,  Kristopher A. Kilian

IPC分类号： B65D81/00 ,  A61B5/00 ,  A01N1/02 ,  C12N15/10

CPC分类号： C12N15/1017

摘要： The present invention provides devices, systems and methods for RNA isolation from biological samples containing white blood cells, such as whole blood. The devices have a device body that includes a first chamber having a first membrane that selectively binds white blood cells, a second chamber having a second membrane that reversibly binds RNA and a plurality of ports that are removably attached to a reagent pack and waste receptacle via a valving system controlled by a control unit.

摘要翻译： 本发明提供了用于从含有白血球（例如全血）的生物样品中分离RNA的装置，系统和方法。 所述装置具有装置主体，其包括具有选择性地结合白细胞的第一膜的第一腔室，具有可逆地结合RNA的第二膜的第二腔室和可移除地连接到试剂盒和废物容器的多个端口， 由控制单元控制的阀门系统。

公开(公告)号：US20090280470A1

公开(公告)日：2009-11-12

申请号：US12280504

申请日：2007-02-15

申请人： Thomas L. Fare ,  Deborah A. Kessler ,  Kristopher A. Killian

发明人： Thomas L. Fare ,  Deborah A. Kessler ,  Kristopher A. Killian

IPC分类号： A01N1/02 ,  C12M1/00

CPC分类号： C12N15/1017

摘要： The present invention provides devices, systems and methods for RNA isolation from biological samples containing white blood cells, such as whole blood. The devices have a device body that includes a first chamber having a first membrane that selectively binds white blood cells, a second chamber having a second membrane that reversibly binds RNA and a plurality of ports that are removably attached to a reagent pack and waste receptacle via a valving system controlled by a control unit.

摘要翻译： 本发明提供了用于从含有白血球（例如全血）的生物样品中分离RNA的装置，系统和方法。 所述装置具有装置主体，其包括具有选择性地结合白细胞的第一膜的第一腔室，具有可逆地结合RNA的第二膜的第二腔室和可移除地连接到试剂盒和废物容器的多个端口， 由控制单元控制的阀门系统。