摘要:
The present invention provides compositions, devices and methods for detecting esterase activity. The present invention also provides devices and methods of detecting esterase inhibitors, for example, organophosphates. In particular, the present invention provides a biosensor comprising Neuropathy Target Esterase (NTE) polypeptides. Further, the present invention relates to medicine, industrial chemistry, agriculture, and homeland security.
摘要:
The present invention provides compositions, devices and methods for detecting esterase activity. The present invention also provides devices and methods of detecting esterase inhibitors, for example, organophosphates. In particular, the present invention provides a biosensor comprising Neuropathy Target Esterase (NTE) polypeptides. Further, the present invention relates to medicine, industrial chemistry, agriculture, and homeland security.
摘要:
The present invention relates to a novel class of nuclear receptor binding agents (NRBAs). The NRBAs are applicable for use in the prevention and/or treatment of a variety of diseases and conditions including prevention and treatment of cancers such as prostate and breast cancer, osteoporosis, hormone-related diseases, inflammatory diseases, oxidative stress related disorders such as Parkinson's and stroke, neurological disorders, ophthalamic disorders, cardiovascular disease, and obesity.
摘要:
Various kinds of nanostructured particles like nanorice and nanospears (i.e., tapered nanorods) are made using polymer nanospheres and ordered porous templates. For example, cylindrical nanopores of anodized alumina membranes are filled with polymer nanoparticles by a solvent assisted nanoinjection. Then the membranes are heated in an oven above the glass transition temperature of the polymer. The nanoparticles coalesce to form nanorods with a controlled aspect ratio and terminal contour. The terminal contour can be shaped in the form of nanorice, nanospears or tapered nanorods.
摘要:
A sensor comprises: a pump cell comprising an inner pump electrode, an outer pump electrode, a pump cell electrolyte layer interposed between the inner pump electrode and the outer pump electrode and a cell isolation layer disposed on the inner pump electrode on a side opposite the pump cell electrolyte, wherein the outer electrode is in fluid communication with a reducing gas. A reference cell is in operable communication with the pump cell, the reference cell comprising an outer reference electrode and an inner reference electrode, and a reference cell electrolyte interposed between the outer reference electrode and the inner reference electrode. A diffusion limiting material flanks both sides of a chamber formed between the cell isolation layer and a cell separation layer, wherein the cell separation layer comprises a via coaxial and in fluid communication with the inner pump electrode, the diffusing limiting material, and the outer reference electrode, and wherein the diffusion limiting material has a gas permeability such that the limiting current of oxygen in air is about 0.05 mA to about 5 mA per cm2 of pump electrode area.
摘要翻译:传感器包括:泵电池,包括内泵电极,外泵电极,介于内泵电极和外泵电极之间的泵电池电解质层,以及设置在内泵电极上的电池隔离层 泵电池电解质,其中外电极与还原气体流体连通。 参考单元与泵浦单元可操作地通信,该参考单元包括外部参考电极和内部参考电极以及介于外部参考电极和内部参考电极之间的参考单元电解质。 扩散限制材料在形成在细胞隔离层和细胞分离层之间的室的两侧侧面,其中细胞分离层包括通孔同轴并与内泵电极,扩散限制材料和外参考物流体连通 电极,并且其中所述扩散限制材料具有气体渗透性,使得空气中的氧气的极限电流为约0.02mA至约5mA / cm 2的泵电极区域。
摘要:
The present invention relates to a novel class of nuclear receptor binding agents (NRBAs). The NRBAs are applicable for use in the prevention and/or treatment of a variety of diseases and conditions including prevention and treatment of cancers such as prostate and breast cancer, osteoporosis, hormone-related diseases, inflammatory diseases, oxidative stress related disorders such as Parkinson's and stroke, neurological disorders, ophthalamic disorders, cardiovascular disease, and obesity.