公开(公告)号：US20060014283A1

公开(公告)日：2006-01-19

申请号：US11162594

申请日：2005-09-15

申请人： Chang Joon YIM ,  Se Won KIM ,  Jung Keun KIM ,  Jong Yeo KIM ,  Hyung Gun KIM ,  Dong Ryung SHIN ,  Yung Mok YU ,  Sung Bin YIM ,  Seon Yle KO ,  Sung Churl LEE

发明人： Chang Joon YIM ,  Se Won KIM ,  Jung Keun KIM ,  Jong Yeo KIM ,  Hyung Gun KIM ,  Dong Ryung SHIN ,  Yung Mok YU ,  Sung Bin YIM ,  Seon Yle KO ,  Sung Churl LEE

IPC分类号： C12N5/08 ,  A61F2/28

CPC分类号： A61L27/3691 ,  A61L2/08 ,  A61L24/0005 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3683 ,  A61L27/3687 ,  A61L2430/02 ,  A61L2430/40

摘要： The present invention relates to inorganic bone graft materials and a method for preparing the bone graft materials. Particularly, the present invention relates to a method for preparing bone graft materials comprises the following steps: collecting cancellous bones from an animal; removing lipids and organic materials from the cancellous bones using organic solvent, sodium hypochlorite and hydrogen peroxide; and sterilizing the cancellous bones wherefrom the lipids and the organic materials are removed. The bone graft materials prepared by the method of the present invention meet requirements for use in bone grafting, including biocompatibility, sterilization, osteoinductivity and osteoconductivity with free from immunogenecity and toxicity to tissue and are suitable for use in osteogenesis and have morphogenesis.

摘要翻译： 本发明涉及无机骨移植材料及其制备方法。 特别地，本发明涉及骨移植材料的制备方法，其特征在于，包括以下步骤：从动物收集松质骨; 使用有机溶剂，次氯酸钠和过氧化氢从松质骨中去除脂质和有机物质; 并对去除脂质和有机材料的松质骨进行消毒。 通过本发明的方法制备的骨移植材料满足骨移植使用的要求，包括生物相容性，灭菌，骨诱导能力和骨传导性，对组织没有免疫原性和毒性，适用于成骨并具有形态发生。

公开(公告)号：US07507254B2

公开(公告)日：2009-03-24

申请号：US11162594

申请日：2005-09-15

申请人： Chang Joon Yim ,  Se Won Kim ,  Jung Keun Kim ,  Jong Yeo Kim ,  Hyung Gun Kim ,  Dong Ryung Shin ,  Yong Mok Yu ,  Sung Bin Yim ,  Seon Yle Ko ,  Sung Churl Lee

发明人： Chang Joon Yim ,  Se Won Kim ,  Jung Keun Kim ,  Jong Yeo Kim ,  Hyung Gun Kim ,  Dong Ryung Shin ,  Yong Mok Yu ,  Sung Bin Yim ,  Seon Yle Ko ,  Sung Churl Lee

IPC分类号： A61F2/28

CPC分类号： A61L27/3691 ,  A61L2/08 ,  A61L24/0005 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3683 ,  A61L27/3687 ,  A61L2430/02 ,  A61L2430/40

摘要： The present invention relates to inorganic bone graft materials and a method for preparing the bone graft materials. Particularly, the present invention relates to a method for preparing bone graft materials comprises the following steps: collecting cancellous bones from an animal; removing lipids and organic materials from the cancellous bones using organic solvent, sodium hypochlorite and hydrogen peroxide; and sterilizing the cancellous bones wherefrom the lipids and the organic materials are removed. The bone graft materials prepared by the method of the present invention meet requirements for use in bone grafting, including biocompatibility, sterilization, osteoinductivity and osteoconductivity with free from immunogenecity and toxicity to tissue and are suitable for use in osteogenesis and have morphogenesis.

摘要翻译： 本发明涉及无机骨移植材料及其制备方法。 特别地，本发明涉及骨移植材料的制备方法，其特征在于，包括以下步骤：从动物收集松质骨; 使用有机溶剂，次氯酸钠和过氧化氢从松质骨中去除脂质和有机物质; 并对去除脂质和有机材料的松质骨进行消毒。 通过本发明的方法制备的骨移植材料满足骨移植使用的要求，包括生物相容性，灭菌，骨诱导能力和骨传导性，对组织没有免疫原性和毒性，适用于成骨并具有形态发生。