公开(公告)号：US20200289406A1

公开(公告)日：2020-09-17

申请号：US16496182

申请日：2018-03-19

申请人： Sachin MITTAL ,  Irina KAZAKEVICH ,  Himanshu BHATTAQCHARJEE ,  Peter BAKKER ,  Luke J. SCHENCK ,  David J. GOLDFARB ,  Amitava MITRA ,  Donna CARROLL ,  Nazia KHAWAJA ,  MERCK SHARP & DOHME CORP. ,  MERCK SHARP & DOHME B. V.

发明人： Sachin Mittal ,  Irina Kazakevich ,  Himanshu Bhattacharjee ,  Peter Bakker ,  Luke Schenck ,  David J. Goldfarb ,  Amitava Mitra ,  Donna Carroll ,  Nazia Khawaja

IPC分类号： A61K9/00 ,  A61K31/4439 ,  A61K47/26 ,  A61K47/22 ,  A61K47/10 ,  A61K47/38

摘要： The instant invention provides pharmaceutical formulations for a long acting injectable drug product comprising a suspension of doravirine for parenteral administration via intramuscular or subcutaneous routes. The drug product can be used for the treatment or prophylaxis of infection by HIV or for the treatment, prophylaxis, or delay in the onset of AIDS (acquired immunodeficiency syndrome) or ARC (AIDS related complex).

公开(公告)号：US11077050B2

公开(公告)日：2021-08-03

申请号：US16496182

申请日：2018-03-19

申请人： MERCK SHARP & DOHME CORP. ,  MERCK SHARP & DOHME B. V. ,  Sachin Mittal ,  Irina Kazakevich ,  Himanshu Bhattacharjee ,  Peter Bakker ,  Luke Schenck ,  David J. Goldfarb ,  Amitava Mitra ,  Donna Carroll ,  Nazia Khawaja

发明人： Sachin Mittal ,  Irina Kazakevich ,  Himanshu Bhattacharjee ,  Peter Bakker ,  Luke Schenck ,  David J. Goldfarb ,  Amitava Mitra ,  Donna Carroll ,  Nazia Khawaja

IPC分类号： A61K31/4439 ,  A61K9/00 ,  A61K47/10 ,  A61K47/22 ,  A61K47/26 ,  A61K47/38 ,  A61K9/10

摘要： The instant invention provides pharmaceutical formulations for a long acting injectable drug product comprising a suspension of doravirine for parenteral administration via intramuscular or subcutaneous routes. The drug product can be used for the treatment or prophylaxis of infection by HIV or for the treatment, prophylaxis, or delay in the onset of AIDS (acquired immunodeficiency syndrome) or ARC (AIDS related complex).