公开(公告)号：US20230172888A1

公开(公告)日：2023-06-08

申请号：US17912711

申请日：2021-03-18

申请人： Myron R. SZEWCZUK ,  ENCYT TECHNOLOGIES, INC.

发明人： Myron R. SZEWCZUK ,  William Warren HARLESS

IPC分类号： A61K31/215 ,  A61K31/616 ,  A61K9/00 ,  A61P31/14

CPC分类号： A61K31/215 ,  A61K31/616 ,  A61K9/0073 ,  A61P31/14

摘要： A method of treating a coronavirus infection involves administering an inhibitor of the Neu1 sialidase-G protein-coupled receptor-Matrix metalloproteinase 9 (Neu1-GPCR-MMP9) signaling platform, in particular administering intravenously or by inhalation to a patient infected with COVID-19 and its variants a therapeutically effective amount of oseltamivir phosphate, preferably in conjunction with the oral administration of aspirin, in order to reduce the symptoms of respiratory compromise and/or prevent Acute Respiratory Distress Syndrome (ARDS).

公开(公告)号：US20180194836A1

公开(公告)日：2018-07-12

申请号：US15539027

申请日：2015-12-22

申请人： ENCYT TECHNOLOGIES, INC.

发明人： William Warren HARLESS

IPC分类号： C07K16/24 ,  A61K39/395 ,  A61K31/727 ,  A61K31/215 ,  A61K45/06 ,  G01N33/68 ,  G01N33/574

CPC分类号： C07K16/24 ,  A61K31/215 ,  A61K31/727 ,  A61K39/3955 ,  A61K45/06 ,  A61K2300/00 ,  G01N33/574 ,  G01N33/6863 ,  G01N2800/54

摘要： There is provided methods for inhibiting metastasis or recurrence of a cancer in a patient after a primary treatment of the patient, and compositions for same. The method comprises administering a therapeutically effective amount of a composition for inhibiting cancer stem cell enrichment In other embodiments, the method comprises administering a therapeutically effective amount of a cancer therapy targeted towards a population of proliferating cancer stem cells in the patient.