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    FABS-IN-TANDEM IMMUNOGLOBULIN AND USES THEREOF
    1.
    发明申请
    FABS-IN-TANDEM IMMUNOGLOBULIN AND USES THEREOF 审中-公开

    公开(公告)号：US20200157249A1

    公开(公告)日：2020-05-21

    申请号：US16720422

    申请日：2019-12-19

    申请人： EpimAb Biotherapeutics, Inc.

    发明人： Chengbin WU

    IPC分类号： C07K16/46 ,  A61K39/395 ,  C07K16/28 ,  A61K45/06 ,  C07K16/24

    摘要： The present invention provides multivalent and multispecific binding proteins that are capable of binding two or more antigens, or two or more epitopes. The present invention also provides methods of making and using such multivalent and multispecific binding proteins, including methods of using such binding proteins for prevention or treatment of various diseases, or for detecting specific antigens in vitro or in vivo.

    Monovalent Asymmetric Tandem Fab Bispecific Antibodies
    3.
    发明申请
    Monovalent Asymmetric Tandem Fab Bispecific Antibodies 审中-公开

    公开(公告)号：US20190177439A1

    公开(公告)日：2019-06-13

    申请号：US16324837

    申请日：2017-08-15

    申请人： EpimAb Biotherapeutics, Inc.

    发明人： Chengbin WU

    IPC分类号： C07K16/46 ,  C07K16/28

    摘要： The invention provides monovalent, asymmetric tandem Fab bispecific antibodies that can bind two epitopes or two antigens, compositions comprising such antibodies, uses of such antibodies, methods of making such antibodies, nucleic acids encoding such antibodies, and host cells comprising such nucleic acids.

    FABS-IN-TANDEM IMMUNOGLOBULIN AND USES THEREOF
    4.
    发明申请
    FABS-IN-TANDEM IMMUNOGLOBULIN AND USES THEREOF 有权

    公开(公告)号：US20230132403A9

    公开(公告)日：2023-04-27

    申请号：US16390912

    申请日：2019-04-22

    申请人： EpimAb Biotherapeutics, Inc.

    发明人： Chengbin Wu

    IPC分类号： C07K16/46 ,  A61K45/06 ,  C07K16/24 ,  C07K16/28

    摘要： The present invention provides multivalent and multispecific binding proteins that are capable of binding two or more antigens, or two or more epitopes. The present invention also provides methods of making and using such multivalent and multispecific binding proteins, including methods of using such binding proteins for prevention or treatment of various diseases, or for detecting specific antigens in vitro or in vivo.

    FABS-IN-TANDEM IMMUNOGLOBULIN AND USES THEREOF
    10.
    发明申请
    FABS-IN-TANDEM IMMUNOGLOBULIN AND USES THEREOF 审中-公开
    FABS-IN-TANDEM免疫球蛋白及其用途

    公开(公告)号：US20160289341A1

    公开(公告)日：2016-10-06

    申请号：US14732088

    申请日：2014-12-24

    申请人： EPIMAB BIOTHERAPEUTICS INC.

    发明人： Chengbin WU

    IPC分类号： C07K16/46 ,  C07K16/24 ,  A61K45/06 ,  C07K16/28 ,  A61K39/395

    摘要： The present invention provides multivalent and multispecific binding proteins that are capable of binding two or more antigens, or two or more epitopes. The present invention also provides methods of making and using such multivalent and multispecific binding proteins, including methods of using such binding proteins for prevention or treatment of various diseases, or for detecting specific antigens in vitro or in vivo.

    摘要翻译： 本发明提供能够结合两种或更多种抗原或两种或多种表位的多价和多特异性结合蛋白。 本发明还提供了制备和使用这种多价和多特异性结合蛋白的方法，包括使用这种结合蛋白来预防或治疗各种疾病或在体外或体内检测特异性抗原的方法。