公开(公告)号：US20080076049A1

公开(公告)日：2008-03-27

申请号：US11535301

申请日：2006-09-26

Applicant: Marko D. Saban ,  Leanne Dawn Murphy ,  Thomas Edward Enright

Inventor： Marko D. Saban ,  Leanne Dawn Murphy ,  Thomas Edward Enright

IPC: C07C229/52 ,  G03G15/02

CPC classification number: G03G5/0614 ,  C07C227/16 ,  C07C229/42

Abstract: Continuous and batch processes for selectively hydrogenating double and/or triple bonds in organic molecules include providing at least one organic molecule containing a double and/or triple bond, providing at least one hydrogen donor molecule, and hydrogenating the double and/or triple bond in the presence of at least one catalyst. Continuous and batch processes for preparing arylamine molecules include selectively hydrogenating double bonds in arylamine compounds by providing at least one organic molecule containing a multiple bond, providing at least one hydrogen donor molecule, and hydrogenating the multiple bond in the presence of at least one catalyst. The continuous and batch processes provide efficient, cost-effective and safe methods for conducting selective hydrogenation reactions in the synthesis of organic molecules, such as charge-transport molecules.

Abstract translation: 用于选择性氢化有机分子中的双键和/或三键的连续和间歇方法包括提供至少一种含有双键和/或三键的有机分子，提供至少一个氢供体分子，并将双键和/或三键氢化 存在至少一种催化剂。 用于制备芳基胺分子的连续和间歇方法包括通过提供至少一个含有多重键的有机分子选择性氢化芳基胺化合物中的双键，提供至少一个氢供体分子，并在至少一种催化剂存在下氢化多重键。 连续和间歇方法提供了在合成有机分子例如电荷传输分子中进行选择性氢化反应的有效，成本有效和安全的方法。

公开(公告)号：US07541060B2

公开(公告)日：2009-06-02

申请号：US10919814

申请日：2004-08-17

Applicant: San-Ming Yang ,  Thomas Edward Enright ,  Aurelian Valeriu Magdalinis ,  Ahmed Abd Alzamly ,  Man-Chung Tam ,  Carol Ann Jennings ,  Peter M. Kazmaier ,  Marko D. Saban ,  Michael Steven Hawkins

Inventor： San-Ming Yang ,  Thomas Edward Enright ,  Aurelian Valeriu Magdalinis ,  Ahmed Abd Alzamly ,  Man-Chung Tam ,  Carol Ann Jennings ,  Peter M. Kazmaier ,  Marko D. Saban ,  Michael Steven Hawkins

IPC: B05D7/00

CPC classification number: G09F9/372 ,  G02B26/026 ,  Y10T428/1405 ,  Y10T428/23 ,  Y10T428/25

Abstract: Disclosed is a technique for producing bichromal balls that are adapted for use in high temperature applications. The bichromal balls find particular application in signs and display devices that can be used in environments in which the temperature exceeds 40° C.

Abstract translation: 公开了一种适用于高温应用的生产双色球的技术。 双色球在符号和显示装置中有特别的应用，可用于温度超过40°C的环境中。

公开(公告)号：US20050255481A1

公开(公告)日：2005-11-17

申请号：US10843717

申请日：2004-05-11

Applicant: Xiao-Jun Ma ,  Edward Enright ,  Mark Erlander

Inventor： Xiao-Jun Ma ,  Edward Enright ,  Mark Erlander

IPC: C12Q1/68 ,  C12Q1/00 ,  C07H21/04 ,  C07K14/72 ,  C12N15/09

CPC classification number: C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/156

Abstract: The invention relates to the identification and use of sequences from expressed progesterone receptor transcripts in relation to breast cancer. In particular, the invention provides the identities of polynucleotide sequences that may be used to identify populations that are positive for estrogen receptor expression. The expressed polynucleotide sequences may be used in the study and/or diagnosis of cells and tissue in breast cancer as well as for the study and/or determination of prognosis of a patient.

Abstract translation: 本发明涉及鉴定和使用与乳腺癌相关的来自表达的孕酮受体转录物的序列。 特别地，本发明提供可用于鉴定对雌激素受体表达呈阳性的群体的多核苷酸序列的身份。 表达的多核苷酸序列可用于研究和/或诊断乳腺癌中的细胞和组织，以及用于研究和/或确定患者的预后。

公开(公告)号：US20120277462A1

公开(公告)日：2012-11-01

申请号：US13095015

申请日：2011-04-27

Applicant: Thomas Edward Enright ,  Pouneh Salehi ,  Kentaro Morimitsu

Inventor： Thomas Edward Enright ,  Pouneh Salehi ,  Kentaro Morimitsu

IPC: C07C67/08

CPC classification number: C07C67/08 ,  C07C2601/14 ,  C07C69/704 ,  C07C69/70

Abstract: A process including reacting at least one organic acid with at least one compound of the formula R—OH, in the presence of an optional catalyst, in a reaction mixture wherein the reaction mixture is substantially free of solvent, to form a reaction product, wherein the reaction product is an ester of citric acid or an ester of tartaric acid; optionally, heating the reaction mixture; and optionally, isolating the reaction product.

Abstract translation: 一种方法，包括使至少一种有机酸与至少一种式R-OH的化合物在任选的催化剂存在下在反应混合物中反应，其中反应混合物基本上不含溶剂，形成反应产物，其中 反应产物是柠檬酸或酒石酸酯的酯; 任选地，加热反应混合物; 并任选地分离反应产物。

公开(公告)号：US07193769B2

公开(公告)日：2007-03-20

申请号：US11128162

申请日：2005-05-13

Applicant: San-Ming Yang ,  Ahmed Hoyshel Alzamly ,  Man-Chung Tam ,  Peter Michael Kazmaier ,  Thomas Edward Enright

Inventor： San-Ming Yang ,  Ahmed Hoyshel Alzamly ,  Man-Chung Tam ,  Peter Michael Kazmaier ,  Thomas Edward Enright

IPC: G02B26/00 ,  G03G17/04

CPC classification number: G02F1/167

Abstract: An electrophoretic display includes a transparent polymeric film including at least one cavity including a first particle species and a second particle species. Application of an electrical field causes the first particle species and the second particle species to separate from one another, and align on opposite sides of the cavity. Subsequent electric field applications cause migration of the first and second particle species, affecting a color state of the display. The electrophoretic display may be fabricated from multiple display cells arranged on a substrate.

Abstract translation: 电泳显示器包括透明聚合物膜，其包括至少一个包含第一颗粒物质和第二颗粒物质的空腔。 施加电场使得第一颗粒物质和第二颗粒物质彼此分离，并在空腔的相对侧对准。 随后的电场应用导致第一和第二颗粒物质的迁移，影响显示器的颜色状态。 电泳显示器可以由布置在基板上的多个显示单元制造。

公开(公告)号：US20060154267A1

公开(公告)日：2006-07-13

申请号：US11089097

申请日：2005-03-24

Applicant: Xiao-Jun Ma ,  Mark Erlander ,  Dennis Sgroi ,  Edward Enright

Inventor： Xiao-Jun Ma ,  Mark Erlander ,  Dennis Sgroi ,  Edward Enright

IPC: G06Q10/00 ,  C12Q1/68 ,  G06Q50/00

CPC classification number: C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/154 ,  C12Q2600/158 ,  G06Q50/22

Abstract: Methods and compositions are provided for the identification of expression signatures in ER+ breast cancer cases, where the signatures correlate with responsiveness, or lack thereof, to treatment with tamoxifen or another antiestrogen agent against breast cancer The signature profiles are identified based upon sampling of reference breast tissue samples from independent cases of breast cancer and provide a reliable set of molecular criteria for predicting the efficacy of treating a subject with breast cancer with tamoxifen or another antiestrogen agent against breast cancer. Additional methods and compositions are provided for predicting responsiveness to tamoxifen or another antiestrogen agent against breast cancer in cases of breast cancer by use of multiple biomarkers. Two biomarkers display increased expression correlated with tamoxifen response while two other biomarkers display decreased expression correlated with tamoxifen response.

Abstract translation: 提供了方法和组合物用于鉴定ER +乳腺癌病例中的表达标志，其中签名与反应性或缺乏相关，与他莫昔芬或另一种针对乳腺癌的抗雌激素剂的治疗相关。基于参考乳腺的抽样来鉴定签名谱 来自乳腺癌独立病例的组织样本，并提供可靠的一组分子标准，用于预测使用他莫昔芬或其他抗雌激素剂对乳腺癌进行乳腺癌治疗的受试者的疗效。 提供了另外的方法和组合物，用于通过使用多种生物标志物来预测在乳腺癌病例中对他莫昔芬或另一种抗雌激素剂对乳腺癌的反应性。 两种生物标志物显示与他莫昔芬反应相关的增加的表达，而另外两种生物标志物显示与他莫昔芬反应相关的降低的表达。

公开(公告)号：US06395445B1

公开(公告)日：2002-05-28

申请号：US09817192

申请日：2001-03-27

Applicant: Alan John Toth ,  Milan Maric ,  Armin R. Völkel ,  Marko D. Saban ,  Thomas Edward Enright

Inventor： Alan John Toth ,  Milan Maric ,  Armin R. Völkel ,  Marko D. Saban ,  Thomas Edward Enright

IPC: G03G9087

CPC classification number: G03G9/0804

Abstract: A process for forming toner particles includes aggregating the toner particles by adding an aggregating agent to a latex emulsion of resin having a colorant mixed therein, the adding being done under adding conditions of agitation and a temperature above a glass transition temperature of the resin, wherein the adding of the aggregating agent comprises first introducing at least about 40% by weight of a total amount of aggregating agent to be added at a rapid introduction rate and subsequently adding a remaining portion of the aggregating agent at a continuous addition rate slower than the rapid introduction rate. The particles are subsequently cooled to a temperature below the glass transition temperature of the resin when particles have been grown to the desired size.

Abstract translation: 用于形成调色剂颗粒的方法包括通过向其中混合有着色剂的树脂的胶乳乳液中加入聚集剂来聚集调色剂颗粒，在搅拌条件和高于树脂的玻璃化转变温度的温度下进行添加，其中 聚集剂的添加包括首先引入至少约40重量％的以快速引入速率加入的总量的总量，然后以比快速的连续添加速率连续添加聚集剂的剩余部分 介绍率。 随后，当颗粒生长至所需尺寸时，随后将颗粒冷却至低于树脂玻璃化转变温度的温度。