公开(公告)号：US5370164A

公开(公告)日：1994-12-06

申请号：US126692

申请日：1993-09-14

申请人： Edwin J. Galloway

发明人： Edwin J. Galloway

IPC分类号： B67D7/02 ,  C12M1/26 ,  B65B3/04

CPC分类号： B67D7/02 ,  B67B7/26 ,  C12M33/06 ,  Y10S604/905

摘要： Means and apparatus for aseptically transferring material between enclosures. Apparatus for transferring the material includes a fluid receiver assembly (12) comprising an adapter (24), and a fitting (93) mounted in the adapter (24). The fitting has a plurality of needle guide channels (86) leading from the outside of the fluid receiver assembly (12) toward the interior of the enclosure (10), and seal means (26) at the ends of the channels (86). Pierceable, self-closing seal means (26) is between ends of each of the channels (86) and the interior of the enclosure. Projected extensions of the channels pass through corresponding holes (40) in the adapter, so that needles (101) inserted into the channels (86) can penetrate the seal means (26) and enter the interior of the enclosure (10). A plurality of needles (101) in a novel needle bundle (95) may be used in making the transfer. An assembly for transferring material between two stationary enclosures comprises a pair of novel needle bundles (295 ) and connecting tubing (266). Methods of transferring materials are taught.

摘要翻译： 用于在外壳之间无菌转移材料的装置和装置。 用于转移材料的装置包括包括适配器（24）的流体接收器组件（12）和安装在适配器（24）中的配件（93）。 配件具有多个从流体接收器组件（12）的外部朝向外壳（10）的内部引导的引导通道（86），以及在通道（86）的端部处的密封装置（26）。 可穿透的自封闭密封装置（26）位于每个通道（86）的端部和外壳的内部之间。 通道的突出延伸通过适配器中的相应的孔（40），使得插入通道（86）中的针头（101）能够穿透密封装置（26）并进入外壳（10）的内部。 新型针束（95）中的多个针（101）可用于进行转印。 用于在两个固定外壳之间转移材料的组件包括一对新颖的针束（295）和连接管（266）。 传授材料的方法。

公开(公告)号：US5269350A

公开(公告)日：1993-12-14

申请号：US39748

申请日：1993-03-30

申请人： Edwin J. Galloway

发明人： Edwin J. Galloway

IPC分类号： B67D7/02 ,  C12M1/26 ,  B65B3/04

CPC分类号： B67D7/02 ,  B67B7/26 ,  C12M33/06 ,  Y10S604/905

摘要： Means and apparatus for aseptically transferring material between enclosures. Apparatus for transferring the material includes a fluid receiver assembly (12) comprising an adapter (24), and a fitting (93) mounted in the adapter (24). The fitting has a plurality of needle guide channels (86) leading from the outside of the fluid receiver assembly (12) toward the interior of the enclosure (10), and seal means (26) at the ends of the channels (86). Pierceable, self-closing seal means (26) is between ends of each of the channels (86) and the interior of the enclosure. Projected extensions of the channels pass through corresponding holes (40) in the adapter, so that needles (101) inserted into the channels (86) can penetrate the seal means (26) and enter the interior of the enclosure (10). A plurality of needles (101) in a novel needle bundle (95) may be used in making the transfer. An assembly for transferring material between two stationary enclosures comprises a pair of novel needle bundles (295 ) and connecting tubing (266). Methods of transferring materials are taught.

摘要翻译： 用于在外壳之间无菌转移材料的装置和装置。 用于转移材料的装置包括包括适配器（24）的流体接收器组件（12）和安装在适配器（24）中的配件（93）。 配件具有多个从流体接收器组件（12）的外部朝向外壳（10）的内部引导的引导通道（86），以及在通道（86）的端部处的密封装置（26）。 可穿透的自封闭密封装置（26）位于每个通道（86）的端部和外壳的内部之间。 通道的突出延伸通过适配器中的相应的孔（40），使得插入通道（86）中的针头（101）能够穿透密封装置（26）并进入外壳（10）的内部。 新型针束（95）中的多个针（101）可用于进行转印。 用于在两个固定外壳之间转移材料的组件包括一对新颖的针束（295）和连接管（266）。 传授材料的方法。

公开(公告)号：US4941517A

公开(公告)日：1990-07-17

申请号：US261020

申请日：1988-10-20

申请人： Edwin J. Galloway

发明人： Edwin J. Galloway

IPC分类号： B67D7/02 ,  C12M1/26

CPC分类号： B67D7/02 ,  B67B7/26 ,  C12M33/06 ,  Y10S604/905

摘要： Apparatus for aseptically transferring material between enclosures. Apparatus for transferring the material includes a fluid receiver assembly (12) comprising an adapter (24), and a fitting (93) mounted in the adapter (24). The fitting has a plurality of needle guide channels (86) leading from the outside of the fluid receiver assembly (12) toward the interior of the enclosure (10), and a seal (26) at the ends of the channels (86). A pierceable, self-closing seal (26) is between ends of each of the channels (86) and the interior of the enclosure. Projected extensions of the channels pass through corresponding holes (40) in the adapter, so that needles (101) inserted into the channels (86) can penetrate the seal (26) and enter the interior of the enclosure (10). A plurality of needles (101) in a novel needle bundle (95) may be used in making the transfer. An assembly for transferring material between two stationary enclosures comprises a pair of novel needle bundles (295) and connecting tubing (266). Methods of transferring materials are taught.

公开(公告)号：US5199473A

公开(公告)日：1993-04-06

申请号：US787545

申请日：1991-11-04

申请人： Edwin J. Galloway

发明人： Edwin J. Galloway

IPC分类号： B67D7/02 ,  C12M1/26

CPC分类号： B67D7/02 ,  C12M33/06 ,  Y10S604/905

摘要： Adapter (24) is adapted to be permanently secured into a tank, or other enclosure. The adapter is configured to receive a replaceable fitting, which is adapted for aseptically transferring fluid material between enclosures. The fitting has a plurality of needle guide channels (86) leading from the outside of the fluid receiver assembly (12) toward the interior of the enclosure (10), and a seal means (26) at the ends of the channels (86). Pierceable, self-closing seal means (26) is between ends of each of the channels (86) and the interior of the enclosure. Projected extensions of the channels pass through corresponding holes (40) in the adapter, so that needles (101) inserted into the channels (86) can penetrate the seal means (26 and enter the interior of the enclosure (10).

摘要翻译： 适配器（24）适于永久地固定在罐或其它外壳中。 适配器被配置为接收可替换的配件，其适于在外壳之间无菌地转移流体材料。 配件具有从流体接收器组件（12）的外部朝向外壳（10）的内部引导的多个针导向通道（86），以及在通道（86）的端部处的密封装置（26） 。 可穿透的自封闭密封装置（26）位于每个通道（86）的端部和外壳的内部之间。 通道的突出延伸通过适配器中的相应的孔（40），使得插入通道（86）中的针（101）可以穿透密封装置（26）并进入外壳（10）的内部。

公开(公告)号：US5343900A

公开(公告)日：1994-09-06

申请号：US63550

申请日：1993-05-18

申请人： Edwin J. Galloway

发明人： Edwin J. Galloway

IPC分类号： B67D7/02 ,  C12M1/26 ,  B65D41/20

CPC分类号： B67B7/26 ,  B67D7/02 ,  C12M33/06 ,  Y10S269/909 ,  Y10S604/905

摘要： This invention provides apparatus and methods for aseptically transferring fluid into or out of a closed aseptic processing system. The apparatus comprises a novel fluid transfer station, including a needle bundle driver, a mounting base mounting the driver to a tank, and a fluid receiver assembly. The needle bundle driver includes a needle bundle holder which holds a needle bundle while the ends of the needles are driven into the tank through the fluid receiver assembly. The cooperation between the needle holder and the needle bundle includes a pair of clamp arms which extend outwardly from the needle bundle, and terminate in top and bottom pods. The top and bottom pods cooperate with the top surface of a support block and a bottom surface with an overhead clamping block, for locking the needle bundle into the needle holder, immobilizing the needle bundle between the clamping block and the support block. With the needle bundle thus immobilized, the needle bundle is driven toward the tank, driving the ends of the needles through the plug and into the tank, thereby establishing fluid communication through the needles, between the needle holder and the tank. Fluid is then passed through the needles and into or out of the tank.

摘要翻译： 本发明提供了用于无菌地将流体输送到或关闭的无菌处理系统中的装置和方法。 该装置包括一个新颖的流体传输站，包括针管驱动器，将驱动器安装到罐的安装基座和流体接收器组件。 针束驱动器包括：针束保持器，其保持针束，同时针的端部通过流体接收器组件被驱动进入罐中。 针保持器和针束之间的配合包括从针束向外延伸的一对夹持臂，并且终止于顶部和底部容器。 顶部和底部荚与支撑块的顶部表面和具有顶部夹持块的底部表面配合，用于将针束锁定到针保持器中，将针束固定在夹紧块和支撑块之间。 通过如此固定针束，将针头朝向箱体驱动，通过塞子驱动针头的端部并进入罐体，从而通过针头在针保持器和罐之间建立流体连通。 然后将流体通过针并进入或离开罐。

公开(公告)号：US5086813A

公开(公告)日：1992-02-11

申请号：US534747

申请日：1990-06-07

申请人： Edwin J. Galloway

发明人： Edwin J. Galloway

IPC分类号： B67D7/02 ,  C12M1/26

CPC分类号： B67D7/02 ,  C12M33/06 ,  Y10S604/905

摘要： Apparatus for aseptically transferring material between enclosures. Apparatus for transferring the material includes a fluid receiver assembly (12) comprising an adapter (24), and a fitting (93) mounted in the adapter (24). The fitting has a plurality of needle guide channels (86) leading from the outside of the fluid receiver assembly (12) toward the interior of the enclosure (10), and a seal (26) at the ends of the channels (86). A pierceable, self-closing seal (26) is between ends of each of the channels (86) and the interior of the enclosure. Projected extensions of the channels pass through corresponding holes (40) in the adapter, so that needles (101) inserted into the channels (86) can penetrate the seal (26) and enter the interior of the enclosure (10). A plurality of needles (101) in a novel needle bundle (95) may be used in making the transfer. An assembly for transferring material between two stationary enclosures comprises a pair of novel needle bundles (295) and connecting tubing (266).

摘要翻译： 用于在外壳之间无菌转移材料的装置。 用于转移材料的装置包括包括适配器（24）的流体接收器组件（12）和安装在适配器（24）中的配件（93）。 配件具有从流体接收器组件（12）的外部朝向外壳（10）的内部引导的多个针导向通道（86），以及在通道（86）的端部处的密封件（26）。 在每个通道（86）的端部和外壳的内部之间，可刺穿的自封闭密封件（26）。 通道的突出延伸通过适配器中的相应的孔（40），使得插入通道（86）中的针头（101）可以穿透密封件（26）并进入外壳（10）的内部。 新型针束（95）中的多个针（101）可用于进行转印。 用于在两个固定外壳之间转移材料的组件包括一对新颖的针束（295）和连接管（266）。