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    IMPROVEMENT TO FUNCTIONAL MODULE FOR THE SELECTIVE APPLICATION OF SUBSTANCES INSIDE FERTILE EGGS
    1.
    发明申请
    IMPROVEMENT TO FUNCTIONAL MODULE FOR THE SELECTIVE APPLICATION OF SUBSTANCES INSIDE FERTILE EGGS 审中-公开

    公开(公告)号：US20180235188A1

    公开(公告)日：2018-08-23

    申请号：US15752834

    申请日：2016-08-16

    申请人： César Da Silva Bastos ,  Roque ARSONVAL WOLF

    发明人： César Da Silva Bastos

    IPC分类号： A01K45/00 ,  C12M3/10 ,  C12M1/32

    CPC分类号： A01K45/007 ,  C12M21/10 ,  C12M33/06

    摘要： An improvement to a functional module for the selective application of substances inside fertile eggs represents an inventive solution in the field of poultry fanning, in particular in the field of poultry breeding, and more specifically in the step of application of vaccines and/or nutrients into fertile eggs by injection, this improvement reducing the risk of violation of biological safety, and ensuring the integrity and survival of the embryo (Em), limiting intra-ovum nutritional supplementation to the amniotic fluid (Li) only, without contact of the needle (a13) with the embryo (Em), and to achieve this condition the module for the selective application of substances inside fertile eggs (Ov) has a structure composed of an injector selector submodule (m1), a selective operation actuation submodule (m2), a speed control submodule (m3) and a common perforator/needle return submodule (m4).

    SEMI-AUTOMATED SAMPLING SYSTEM FOR ASEPTIC SAMPLING
    4.
    发明申请
    SEMI-AUTOMATED SAMPLING SYSTEM FOR ASEPTIC SAMPLING 审中-公开
    用于自动采样的半自动采样系统

    公开(公告)号：US20160123848A1

    公开(公告)日：2016-05-05

    申请号：US14529201

    申请日：2014-10-31

    申请人： General Electric Company

    发明人： Weston Blaine Griffin ,  Chengkun Zhang ,  Kenneth Roger Conway ,  Reginald Donovan Smith

    IPC分类号： G01N1/14 ,  G01N33/48 ,  G01N35/10

    CPC分类号： G01N1/14 ,  C12M29/12 ,  C12M33/06 ,  C12M37/02 ,  C12M41/00

    摘要： A semi-automated sampling assembly configured for aseptic sampling at one or more instances from a sample source having a biological inoculum is provided. The semi-automated sampling assembly includes a sampling conduit, a recovery conduit, one or more sampling kits, and a pumping device. The sampling conduit includes a first port and a second port, where the first port of the sampling conduit is configured to be operatively coupled to the sample source. Further, the recovery conduit includes a first port and a second port, where the first port of the recovery conduit is configured to be operatively coupled to the sample source. Also, the second port of the recovery conduit is operatively coupled to at least a portion of the sampling conduit. Moreover, the one or more sampling kits are operatively coupled to the sampling conduit, and the pumping device is operatively coupled to the sampling conduit.

    摘要翻译： 提供了一种半自动采样组件，其被配置为在具有生物接种物的样品源的一个或多个实例处进行无菌取样。 半自动采样组件包括采样导管，回收管道，一个或多个采样套件以及泵送装置。 采样导管包括第一端口和第二端口，其中采样导管的第一端口被配置为可操作地耦合到采样源。 此外，回收管道包括第一端口和第二端口，其中回收管道的第一端口被配置为可操作地耦合到采样源。 此外，回收管道的第二端口可操作地联接到采样管道的至少一部分。 此外，一个或多个采样套件可操作地耦合到采样导管，并且泵送装置可操作地耦合到采样导管。

    SYSTEMS AND METHODS FOR ASEPTIC SAMPLING
    5.
    发明申请
    SYSTEMS AND METHODS FOR ASEPTIC SAMPLING 审中-公开
    用于自由采样的系统和方法

    公开(公告)号：US20160053296A1

    公开(公告)日：2016-02-25

    申请号：US14462594

    申请日：2014-08-19

    申请人： General Electric Company

    发明人： Chengkun Zhang ,  Kenneth Roger Conway ,  Donald Joseph Buckley ,  Eugene Pauling Boden ,  Weston Blaine Griffin ,  Anshika Bajaj ,  Reginald Donovan Smith ,  Zhipeng Zhang

    IPC分类号： C12Q1/24 ,  B01L3/00

    CPC分类号： C12M23/40 ,  B01L3/561 ,  B01L2200/141 ,  C12M33/06 ,  C12M37/02 ,  G01N1/18

    摘要： A sampling assembly configured to be coupled to a sample source is provided. The sampling assembly is configured to facilitate aseptic sampling at one or more instances in time. The sampling assembly includes a first conduit having a first port and a second port, where the first port is configured to be coupled to the sample source, and where the second port is configured to be hermetically sealed. The sampling assembly further includes a plurality of sub-conduits having corresponding sub-ports, where each of the plurality of sub-conduits is operatively coupled to the first conduit at respective connection points, and where each of the sub-ports is in fluidic communication with the first conduit. Moreover, the sampling assembly includes a plurality of sampling kits, where each sampling kit of the plurality of sampling kits is operatively connected to a respective sub-port of a corresponding sub-conduit.

    摘要翻译： 提供了一种被配置为耦合到采样源的采样组件。 采样组件被配置为便于在一个或多个实例的时间进行无菌取样。 采样组件包括具有第一端口和第二端口的第一导管，其中第一端口被配置为耦合到采样源，并且其中第二端口被配置为气密密封。 采样组件还包括具有对应子端口的多个子导管，其中多个子导管中的每一个在相应的连接点处可操作地耦合到第一导管，并且其中每个子端口处于流体连通 与第一个导管。 此外，采样组件包括多个采样套件，其中多个采样套件的每个采样套件可操作地连接到相应副导管的相应子端口。

    AUTOMATIC BIOLOGICAL SAMPLE PURIFICATION APPARATUS EQUIPPED WITH MAGNETIC FILED APPLYING PART, METHOD OF EXTRACTING TARGET SUBSTANCE FROM BIOLOGICAL SAMPLE, AND PROTEIN EXPRESSION AND PURIFICATION METHOD
    7.
    发明申请
    AUTOMATIC BIOLOGICAL SAMPLE PURIFICATION APPARATUS EQUIPPED WITH MAGNETIC FILED APPLYING PART, METHOD OF EXTRACTING TARGET SUBSTANCE FROM BIOLOGICAL SAMPLE, AND PROTEIN EXPRESSION AND PURIFICATION METHOD 有权
    自动生物样品净化装置配备磁性填充应用部分，从生物样品中提取目标物质的方法和蛋白质表达和纯化方法

    公开(公告)号：US20130043191A1

    公开(公告)日：2013-02-21

    申请号：US13643395

    申请日：2011-04-29

    申请人： Han-oh Park ,  Jong-kab Kim ,  Yang-won Lee ,  Jong-hoon Kim

    发明人： Han-oh Park ,  Jong-kab Kim ,  Yang-won Lee ,  Jong-hoon Kim

    IPC分类号： B03C1/02

    CPC分类号： C12M33/06 ,  C12N15/1003

    摘要： Disclosed is an automatic purification apparatus for isolating target substances from multiple biological samples, and more particularly to an automatic biological sample purification apparatus equipped with a magnetic field applying part, in which the magnetic field applying part for purifying biological samples and a heating part are integrally formed with each other so as to be movable up and down.Further, disclosed is a method of extracting a target substance from the biological sample using the automatic biological sample purification apparatus equipped with the magnetic field applying part.

    摘要翻译： 公开了一种用于从多个生物样品中分离目标物质的自动净化装置，更具体地，涉及一种具有磁场施加部的自动生物样品净化装置，其中用于纯化生物样品的磁场施加部和加热部一体化 彼此形成为可上下移动。 此外，公开了使用配备有磁场施加部的自动生物样品净化装置从生物样品中提取目标物质的方法。

    CELL CULTURE APPARATUS
    9.
    发明申请
    CELL CULTURE APPARATUS 有权
    细胞培养装置

    公开(公告)号：US20120252110A1

    公开(公告)日：2012-10-04

    申请号：US13432658

    申请日：2012-03-28

    申请人： Mitsuhiro OURA ,  Teruo OKANO ,  Tatsuya SHIMIZU ,  Hirotsugu KUBO ,  Sunao TAKEDA

    发明人： Mitsuhiro OURA ,  Teruo OKANO ,  Tatsuya SHIMIZU ,  Hirotsugu KUBO ,  Sunao TAKEDA

    IPC分类号： C12M1/26 ,  C12M1/34

    CPC分类号： C12M33/06 ,  C12M29/26 ,  C12M41/14 ,  C12M41/48

    摘要： A cell culture apparatus includes: an isolator in which a sterile space accommodating a cell incubator filled with a culture solution containing cells to be cultured is disposed; a sampling unit configured to sample the culture solution in the cell incubator; a delivery flow path through which an inside of the sterile space and an outside of the sterile space communicate with each other, the delivery flow path configured to limit a flow in the delivery flow path to a direction that is directed from the inside of the sterile space toward the outside of the sterile space; and a culture solution delivering section configured to deliver the sampled culture solution to the outside of the sterile space via the delivery flow path.

    摘要翻译： 细胞培养装置包括：隔离器，其中设置容纳装有包含待培养细胞的培养液的细胞培养箱的无菌空间; 取样单元，其构造为对细胞培养器中的培养液进行取样; 输送流动路径，无菌空间的内部和无菌空间的外部通过其彼此连通，输送流路被配置为将输送流动路径中的流动限制到从无菌空间的内部指向的方向 空间朝无菌空间外面; 以及培养液输送部，其构造成经由所述输送流路将取样的培养液输送到所述无菌空间的外部。

    AUTOMATED ASEPTIC LIQUID COLLECTION WORKSTATIONS AND COLLECTION DEVICES THEREFORE
    10.
    发明申请
    AUTOMATED ASEPTIC LIQUID COLLECTION WORKSTATIONS AND COLLECTION DEVICES THEREFORE 有权
    自动液体收集工作站和收集装置

    公开(公告)号：US20120138156A1

    公开(公告)日：2012-06-07

    申请号：US13118891

    申请日：2011-05-31

    申请人： Jan Hofman ,  Cleem Diemers

    发明人： Jan Hofman ,  Cleem Diemers

    IPC分类号： F03B11/00

    CPC分类号： G01N1/2035 ,  C12M33/06 ,  C12M37/00 ,  G01N1/18 ,  G01N2001/1427 ,  G01N2001/205 ,  G01N2001/2071 ,  Y10T137/0324 ,  Y10T137/8593 ,  Y10T137/85978 ,  Y10T436/2575

    摘要： An automated liquid collection workstation is provided. The workstation includes a processor, a peristaltic pump, a valve actuator, and an algorithm. The peristaltic pump and the valve actuator are in electrical communication with the processor. The valve actuator can move a plurality of valves, when disposed therein, among an off position, a flush position, and a collection position. The algorithm is resident on the processor and is configured to: move all of the valves to the off position and place the pump in an off state when no sampling or flushing is required, move all of the valves to the flush position and place the pump in an on state for a predetermined flush time period when flushing is required, and move a respective one of the valves to the collection position, move any of the valves upstream of the respective valve to the flush position, and place the pump to the on state for a predetermined collection time period when collection is required.

    摘要翻译： 提供自动化液体收集工作站。 工作站包括处理器，蠕动泵，阀致动器和算法。 蠕动泵和阀门执行器与处理器电连通。 阀门致动器可以在关闭位置，冲洗位置和收集位置之间移动多个阀。 该算法驻留在处理器上，并且被配置为：当不需要采样或冲洗时，将所有阀移动到关闭位置并将泵置于关闭状态，将所有阀移动到冲洗位置并将泵 在需要冲洗时处于预定冲洗时间段的打开状态，并且将相应的一个阀移动到收集位置，将相应阀门上游的任何阀移动到冲洗位置，并将泵置于 在需要收集时预定收集时间段。