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公开(公告)号：US07408046B2
公开(公告)日：2008-08-05
申请号：US10882054
申请日：2004-06-30
申请人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
发明人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
IPC分类号： C07F5/00
CPC分类号： A61K51/0482 , A61K51/0478 , A61K51/0489 , Y10S514/836
摘要： The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
摘要翻译： 本发明涉及一种抑制骨髓（BM）的治疗方法，并且治疗在诸如癌症，骨髓增生性疾病，自身免疫性疾病，传染病，代谢疾病或遗传疾病之类的骨附近或附近产生的病症，组合物具有作为其活性成分的组合物 与螯合剂如大环氨基膦酸络合的放射性核素。
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公开(公告)号：US06767531B2
公开(公告)日：2004-07-27
申请号：US10014335
申请日：2001-12-11
申请人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
发明人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
IPC分类号： A61K5100
CPC分类号： A61K51/0482 , A61K51/0478 , A61K51/0489 , Y10S514/836
摘要： The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
摘要翻译： 本发明涉及一种抑制骨髓（BM）的治疗方法，并且治疗在诸如癌症，骨髓增生性疾病，自身免疫性疾病，传染病，代谢疾病或遗传疾病之类的骨附近或附近产生的病症，组合物具有作为其活性成分的组合物 与螯合剂如大环氨基膦酸络合的放射性核素。
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公开(公告)号：US07696331B2
公开(公告)日：2010-04-13
申请号：US12142664
申请日：2008-06-19
申请人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
发明人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
IPC分类号： C07F5/00
CPC分类号： A61K51/0482 , A61K51/0478 , A61K51/0489 , Y10S514/836
摘要： The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
摘要翻译： 本发明涉及一种抑制骨髓（BM）的治疗方法，并且治疗在诸如癌症，骨髓增生性疾病，自身免疫性疾病，传染病，代谢疾病或遗传疾病之类的骨附近或附近产生的病症，组合物具有作为其活性成分的组合物 与螯合剂如大环氨基膦酸络合的放射性核素。
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公开(公告)号：US20090136419A1
公开(公告)日：2009-05-28
申请号：US12142664
申请日：2008-06-19
申请人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
发明人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
CPC分类号： A61K51/0482 , A61K51/0478 , A61K51/0489 , Y10S514/836
摘要： The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
摘要翻译： 本发明涉及一种抑制骨髓（BM）的治疗方法，并且治疗在诸如癌症，骨髓增生性疾病，自身免疫性疾病，传染病，代谢疾病或遗传疾病之类的骨附近或附近产生的病症，组合物具有作为其活性成分的组合物 与螯合剂如大环氨基膦酸络合的放射性核素。
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公开(公告)号：US07378077B2
公开(公告)日：2008-05-27
申请号：US11485183
申请日：2006-07-12
申请人： Alan R. Fritzberg , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
发明人： Alan R. Fritzberg , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
CPC分类号： A61K51/0482 , A61K51/0478 , A61K51/0489 , Y10S514/836
摘要： The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
摘要翻译： 本发明涉及一种抑制骨髓（BM）的治疗方法，并且治疗在诸如癌症，骨髓增生性疾病，自身免疫性疾病，传染病，代谢疾病或遗传疾病之类的骨附近或附近产生的病症，组合物具有作为其活性成分的组合物 与螯合剂如大环氨基膦酸络合的放射性核素。
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公开(公告)号：US07070759B2
公开(公告)日：2006-07-04
申请号：US11041828
申请日：2005-01-24
申请人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
发明人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
CPC分类号： A61K51/0482 , A61K51/0478 , A61K51/0489 , Y10S514/836
摘要： The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
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公开(公告)号：US07097823B2
公开(公告)日：2006-08-29
申请号：US10784476
申请日：2004-02-23
申请人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
发明人： Alan R. Fritzberg , Paul G. Abrams , Lauren Marie Tatalick , Kent R. Thoelke , James Kyle Bryan , Mark D. Hylarides , Elizabeth K. John
CPC分类号： A61K51/0482 , A61K51/0478 , A61K51/0489 , Y10S514/836
摘要： The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.
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