公开(公告)号：US20140319740A1

公开(公告)日：2014-10-30

申请号：US14328807

申请日：2014-07-11

Applicant: Elizabeth L. Dirk ,  Shawn Dirk ,  Kirsten Cicotte

Inventor： Elizabeth L. Dirk ,  Shawn Dirk ,  Kirsten Cicotte

IPC: D04H1/728 ,  D01D5/00

CPC classification number: D04H1/728 ,  D01D5/0007 ,  D01D5/003 ,  D01D5/0092 ,  D01D5/38 ,  D01F6/62 ,  D04H1/4326 ,  D10B2321/08 ,  Y10T428/2915 ,  Y10T442/60

Abstract: Methods and apparatus for forming non-woven fiber mats from polymers and monomers that are traditionally difficult to use for fiber formation are shown and described. Applicable techniques include electrospinning and other traditional fiber formation methods. Suitable polymers and monomers include those having low molecular weight, a low melting point, and/or a low glass transition temperature.

Abstract translation: 显示和描述了用于形成传统上难以用于纤维形成的聚合物和单体的无纺纤维毡的方法和设备。 适用的技术包括静电纺丝和其他传统的纤维形成方法。 合适的聚合物和单体包括具有低分子量，低​​熔点和/或低玻璃化转变温度的那些。

公开(公告)号：US09816214B2

公开(公告)日：2017-11-14

申请号：US14328807

申请日：2014-07-11

Applicant: Elizabeth L Dirk ,  Shawn Dirk ,  Kirsten Cicotte

Inventor： Elizabeth L Dirk ,  Shawn Dirk ,  Kirsten Cicotte

IPC: D04H1/728 ,  D01D5/00 ,  D04H1/4326 ,  D01D5/38 ,  D01F6/62

CPC classification number: D04H1/728 ,  D01D5/0007 ,  D01D5/003 ,  D01D5/0092 ,  D01D5/38 ,  D01F6/62 ,  D04H1/4326 ,  D10B2321/08 ,  Y10T428/2915 ,  Y10T442/60

Abstract: Methods and apparatus for forming non-woven fiber mats from polymers and monomers that are traditionally difficult to use for fiber formation are shown and described. Applicable techniques include electrospinning and other traditional fiber formation methods. Suitable polymers and monomers include those having low molecular weight, a low melting point, and/or a low glass transition temperature.

公开(公告)号：US20160152766A1

公开(公告)日：2016-06-02

申请号：US14956521

申请日：2015-12-02

Applicant: Elizabeth L Dirk ,  Shawn Dirk ,  Kirsten Cicotte

Inventor： Elizabeth L Dirk ,  Shawn Dirk ,  Kirsten Cicotte

IPC: C08G63/52

CPC classification number: C08G63/52 ,  C08F222/10

Abstract: A variety of polymers and copolymers suitable for use as biologically compatible constructs and, as a non-limiting specific example, in the formation of degradable tissue scaffolds as well methods for synthesizing these polymers and copolymers are described. The polymers and copolymers have degradation rates that are substantially faster than those of previously described polymers suitable for the same uses. Copolymers having a synthesis route which enables one to fine tune the degradation rate by selecting the specific stoichiometry of the monomers in the resulting copolymer are also described. The disclosure also provides a novel synthesis route for maleoyl chloride which yields monomers suitable for use in the copolymer synthesis methods described herein.

Abstract translation: 描述适合用作生物相容性构建体的多种聚合物和共聚物，以及作为非限制性具体实例的可降解组织支架的形成以及用于合成这些聚合物和共聚物的方法。 聚合物和共聚物的降解速率明显快于适用于相同用途的前述聚合物的降解速率。 还描述了具有能够通过选择所得共聚物中单体的特定化学计量来微调降解速率的合成途径的共聚物。 本公开还提供了一种用于马来酰氯的新型合成路线，其产生适用于本文所述共聚物合成方法的单体。